DiffHic package - heatmap generation from normalized data
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@rulicosentino-8154
Last seen 5.8 years ago
Germany

Hi,

I would like to know how to generate an interaction heatmap, like the one is generated with plotPlaid, after normalizing the input data. More precisely, I would like to generate a heatmap after iterative correction of interaction intensities (correctedContact).

Thanks,

diffhic • 777 views
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Aaron Lun ★ 27k
@alun
Last seen 2 hours ago
The city by the bay

Use plotDI and give it the normalized interaction intensities for each bin pair as fc. It's probably best to log-transform the interaction intensities and rescale them to have a mean of zero, in order to get a sensible visualization. High-intensity interactions will be red, and low-intensity interactions will be blue.