The previous problem is solved,thanks for your effort.I have a question the plot that is generated for Mutation spectrum using this function -
plotMutationSpectrum(sca_motifs, "study") gives Contribution vs Motif plot.What does Contribution means here?
Another Question regarding Mutation signature plot is that while generating the plot multiple times(generated 5 times),we are getting different results(results are not similar in all 5 plots) using this function-
plotSignatures(sigs_nmf) + ggtitle("Somatic Signatures: NMF - Barchart")
Why this is occurring,not able to find out.Need your help.Looking for your response.