in my DMRcate results concerning two analyses I've very small meanpvals.
In the first analysis the smallest meanpval is 2.65e-210 with cutoff of 7.18e-21;
in the second one the smallest meanpval is 9.19e-305 with cutoff of 1.19e-12 and there are about 40 DMRs with meanpval exactly 0.
The PCA plot shows clearly differences between the groups but I was wondering if something bias the method in my analyses, since there are such small values.
Thanks in advance, Regards