I am using maSigPro for an NGS time series analysis on 10 different patients at 5 different time points T0,T1,T2,T3 and T4 (=50 samples in total). We introduce an insult after T0 and I want to do a trend analysis pre and post insult using masigpro across the time-points. I was wondering if it is possible to add patient ID as a random factor is maSigpro to remove the variation due to the patient? We can do this in DESeq2 and Limma (Voom) but not sure if this is possible in maSigPro?
Thanks in advance.