CRLMM: Which array type work with which annotation package
1
0
Entering edit mode
komal.rathi ▴ 80
@komalrathi-9163
Last seen 4 weeks ago
United States

Disclaimer: Crossposted on Biostars.

I am using the CRLMM package. We have about 21000 IDATs that belong to the following array types:

Array                    Annotation Package (Guess)
HumanHap550              human550v3b
Human610-Quad            human610quadv1b
HumanOmniExpress-24v1-1  Not sure
HumanOmniExpress-24v1-0  Not sure
HumanOmniExpress-12v1-1  humanomniexpress12v1b
HumanOmniExpress-12v1-0  humanomniexpress12v1b

These are the annotation packages supported by CRLMM:

> validCdfNames()
 [1] "genomewidesnp6"          "genomewidesnp5"         
 [3] "human1mv1c"              "human370v1c"            
 [5] "human650v3a"             "human610quadv1b"        
 [7] "human660quadv1a"         "human370quadv3c"        
 [9] "human550v3b"             "human1mduov3b"          
[11] "humanomni1quadv1b"       "humanomni25quadv1b"     
[13] "humanomni258v1a"         "humanomni258v1p1b"      
[15] "humanomni5quadv1b"       "humanomniexpress12v1b"  
[17] "humanimmuno12v1b"        "humancytosnp12v2p1h"    
[19] "humanexome12v1p2a"       "humanomniexpexome8v1p1b"

I am not certain which annotation packages (validCdfNames) will go with the human omni express arrays mentioned above. Any help would be much appreciated.

Thanks!

crlmm • 1.0k views
ADD COMMENT
0
Entering edit mode
Matthew Ritchie ▴ 1000
@matthew-ritchie-650
Last seen 5 months ago
Australia

Thanks for your question. For the HumanOmniExpress-24v1-1 and HumanOmniExpress-24v1-0 we don't have a package at this stage unfortunately.

We are putting together a work around for cases like this, where the user specifies the annotation and sets  cdfName="nopackage" but I've just identified some bugs in this code, so need to test it out a little more before committing it to Bioconductor.

ADD COMMENT
0
Entering edit mode

Thanks for the response. A documentation on the columns required in the custom annotation would be really helpful as well. 

ADD REPLY
0
Entering edit mode

Hi Matthew

I was wondering if you have been able to release the workaround?  I have HumanOmniExpress-24v1-2 data I would love to process in crlmm.  Thanks!

 

ADD REPLY
0
Entering edit mode

Hello,

I would also be interested to know whether I could use the "HumanOmni2-5-8v1-3", as there is as far as I can see no package for that availible yet? How could I import those arrays?

ADD REPLY
0
Entering edit mode

Was it solved? Thanks in advance

ADD REPLY

Login before adding your answer.

Traffic: 256 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6