Question: CRLMM: Which array type work with which annotation package
gravatar for komal.rathi
13 months ago by
United States
komal.rathi30 wrote:

Disclaimer: Crossposted on Biostars.

I am using the CRLMM package. We have about 21000 IDATs that belong to the following array types:

Array                    Annotation Package (Guess)
HumanHap550              human550v3b
Human610-Quad            human610quadv1b
HumanOmniExpress-24v1-1  Not sure
HumanOmniExpress-24v1-0  Not sure
HumanOmniExpress-12v1-1  humanomniexpress12v1b
HumanOmniExpress-12v1-0  humanomniexpress12v1b

These are the annotation packages supported by CRLMM:

> validCdfNames()
 [1] "genomewidesnp6"          "genomewidesnp5"         
 [3] "human1mv1c"              "human370v1c"            
 [5] "human650v3a"             "human610quadv1b"        
 [7] "human660quadv1a"         "human370quadv3c"        
 [9] "human550v3b"             "human1mduov3b"          
[11] "humanomni1quadv1b"       "humanomni25quadv1b"     
[13] "humanomni258v1a"         "humanomni258v1p1b"      
[15] "humanomni5quadv1b"       "humanomniexpress12v1b"  
[17] "humanimmuno12v1b"        "humancytosnp12v2p1h"    
[19] "humanexome12v1p2a"       "humanomniexpexome8v1p1b"

I am not certain which annotation packages (validCdfNames) will go with the human omni express arrays mentioned above. Any help would be much appreciated.


ADD COMMENTlink modified 13 months ago by Matthew Ritchie660 • written 13 months ago by komal.rathi30
gravatar for Matthew Ritchie
13 months ago by
Matthew Ritchie660 wrote:

Thanks for your question. For the HumanOmniExpress-24v1-1 and HumanOmniExpress-24v1-0 we don't have a package at this stage unfortunately.

We are putting together a work around for cases like this, where the user specifies the annotation and sets  cdfName="nopackage" but I've just identified some bugs in this code, so need to test it out a little more before committing it to Bioconductor.

ADD COMMENTlink written 13 months ago by Matthew Ritchie660

Thanks for the response. A documentation on the columns required in the custom annotation would be really helpful as well. 

ADD REPLYlink written 13 months ago by komal.rathi30

Hi Matthew

I was wondering if you have been able to release the workaround?  I have HumanOmniExpress-24v1-2 data I would love to process in crlmm.  Thanks!


ADD REPLYlink written 8 months ago by j.holbrook0


I would also be interested to know whether I could use the "HumanOmni2-5-8v1-3", as there is as far as I can see no package for that availible yet? How could I import those arrays?

ADD REPLYlink written 7 months ago by felix0
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