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Question: SC3 with latent variable corrected counts
1
gravatar for Mark
18 months ago by
Mark10
Imperial College London
Mark10 wrote:

I was just wondering if it's valid to perform SC3 clustering on latent variable normalised counts obtained for example from RUVSeq's RUVg or similar methods?

 

Thanks a lot,

Mark

ADD COMMENTlink modified 18 months ago by Vladimir Kiselev130 • written 18 months ago by Mark10
2
gravatar for Vladimir Kiselev
18 months ago by
Sanger Institute, Cambridge, UK
Vladimir Kiselev130 wrote:

Hi Mark,

Thanks for your question!

Yes, it is valid. SC3 treats RUV normalised counts the same way as counts normalised by any type of the size factor normalisations.

Cheers,

Vladimir

ADD COMMENTlink written 18 months ago by Vladimir Kiselev130
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