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jjalmagro
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@jjalmagro-12099
Last seen 5.6 years ago

Hello,

I am stuck with one of the steps required to calculated DMRs using BiSeq. I have modeled the methylation under the beta regression using the group and gender as explanatory variables. However, when I reach the step where the beta regression has to be calculated for the resampled data, I am not sure about how it should be resampled when there are more than one explanatory variable. Do I have to resample just the group variable or both of them?

Regards,

Jose

Hello Katja,

I get it know, thank you. One final question, I have modeled the methylation using 12 cases and 6 controls. Do I have to use just 6 cases and the 6 controls to have the same number of samples in each group?

Regards,

Jose