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Lidia • 0
@9619883e
Last seen 4 weeks ago
Malta

Dear all, I am doing research in bioinformatics and I was given digital data (RNA-seq) and 9 samples .1 sample is control , 3 samples related to 1 type of cancer and 5 samples related to another type of cancer .My question is : can I use 1 sample and still use DESeq2 ? For example I use 3 samples ( one type of tumor) and compare it with 1 control sample or it is impossible ? Thank you very much in advance , kindly replay .Do you have an email for correspondence please? with best regards Lidia

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@mikelove
Last seen 6 hours ago
United States

Yes you can use DESeq2 as long as some group has replicates. However, as with all statistical methods, your power will be very low.