Reversing DEseq2 normalization
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@9012138b
Last seen 15 days ago
United States

hi,

I am trying to merge GEo data from different authors, most are in raw counts and I would convert to log CPM, but one dataset is in Normalized count (DESeq Normalization). Which package can I use to undo the normalization or convert to CPM or do I just merge CPM with DESeq normalization.

Thanks

DESeq2 Normalization RNASeq • 120 views
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@mikelove
Last seen 8 hours ago
United States

I would go from normalized counts to CPM. I believe providing the normalized counts to edgeR's cpm will be fine.

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