Hi, when I use "GDCprepare" function, I had a such error:
library(TCGAbiolinks) LUAD_methy <- GDCquery( project = "TCGA-LUAD", data.category = "DNA Methylation", data.type = "Masked Intensities", platform = "Illumina Human Methylation 450", # Illumina Human Methylation 450 legacy = FALSE) GDCdownload(LUAD_methy) GDCprepare(LUAD_methy,save = T,save.filename="LUAD_METHY_idat.Rdata") Processing IDATs with Sesame - http://bioconductor.org/packages/sesame/ Running opensesame - applying quality masking and nondetection masking (threshold P-value 0.05) Please cite: doi: 10.1093/nar/gky691 and 10.1093/nar/gkt090 This might take a while.... Error: BiocParallel errors 1 remote errors, element index: 1 506 unevaluated and other errors first remote error: Error in stopAndCache(title): | File idatSignature needs to be cached to be used in sesame. | Please make sure you have updated ExperimentHub and try | > sesameDataCache() | to retrieve and cache needed sesame data.
When I run sesameDataCache(), it hasn't run for several hours. Is there a good solution? thank you