Hi, we have RNAseq data with some evident batch effect. We wont to correct this to have batch effect corrected counts to be then used in DESeq. The idea is to have all the subsequent analyses (e.g. PCA, hierarchical clustering, GSEA) that use DESeq normalized counts already compenseted for the batch effect. Is this possible? What is the best tool to remove batch effect on raw counts to obtain data to be then used in DESeq differential expression analysis? Thank you in advance for the help.