DESeq2 - I can't get the library to load
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v.chin • 0
@vchin-12532
Last seen 7.1 years ago
I am new to all this!  I can download DESeq2 using 
source("https://bioconductor.org/biocLite.R")
biocLite("DESeq2")

but when I go to load the libraries I get this error:

Error in loadNamespace(j <- i[[1L]], c(lib.loc, .libPaths()), versionCheck = vI[[j]]) : 
  there is no package called ‘data.table’
Error: package or namespace load failed for ‘DESeq2’

Can anyone help?

Venessa.

SessionInfo:

R version 3.3.2 (2016-10-31)
Platform: x86_64-apple-darwin13.4.0 (64-bit)
Running under: macOS Sierra 10.12.3

locale:
[1] en_AU.UTF-8/en_AU.UTF-8/en_AU.UTF-8/C/en_AU.UTF-8/en_AU.UTF-8

attached base packages:
[1] stats4    parallel  stats     graphics  grDevices utils    
[7] datasets  methods   base     

other attached packages:
 [1] BiocInstaller_1.24.0       SummarizedExperiment_1.4.0
 [3] GenomicRanges_1.26.3       GenomeInfoDb_1.10.3       
 [5] IRanges_2.8.1              S4Vectors_0.12.1          
 [7] edgeR_3.16.5               limma_3.30.12             
 [9] Biobase_2.34.0             BiocGenerics_0.20.0       

loaded via a namespace (and not attached):
 [1] locfit_1.5-9.1      splines_3.3.2       lattice_0.20-34    
 [4] colorspace_1.3-2    htmltools_0.3.5     base64enc_0.1-3    
 [7] survival_2.40-1     foreign_0.8-67      BiocParallel_1.8.1 
[10] RColorBrewer_1.1-2  plyr_1.8.4          stringr_1.2.0      
[13] zlibbioc_1.20.0     munsell_0.4.3       gtable_0.2.0       
[16] htmlwidgets_0.8     latticeExtra_0.6-28 knitr_1.15.1       
[19] htmlTable_1.9       Rcpp_0.12.9         acepack_1.4.1      
[22] scales_0.4.1        backports_1.0.5     checkmate_1.8.2    
[25] XVector_0.14.0      gridExtra_2.2.1     ggplot2_2.2.1      
[28] digest_0.6.12       stringi_1.1.2       grid_3.3.2         
[31] tools_3.3.2         bitops_1.0-6        magrittr_1.5       
[34] lazyeval_0.2.0      RCurl_1.95-4.8      tibble_1.2         
[37] Formula_1.2-1       cluster_2.0.5       Matrix_1.2-8       
[40] assertthat_0.1      rpart_4.1-10        nnet_7.3-12    

DESeq2 • 8.3k views
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@martin-morgan-1513
Last seen 10 hours ago
United States

It should not be necessary (R should take care of loading dependencies) but try installating data.table also

source("https://bioconductor.org/biocLite.R")
biocLite("data.table")
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I'm having a similar error, but different package:

library("DESeq2") Error: package or namespace load failed for ‘DESeq2’ in loadNamespace(j <- i[[1L]], c(lib.loc, .libPaths()), versionCheck = vI[[j]]): there is no package called ‘Hmisc’

Installing Hmisc as suggested above did not solve the issue.

sessionInfo() R version 3.6.3 (2020-02-29) Platform: x86_64-apple-darwin15.6.0 (64-bit) Running under: macOS Catalina 10.15.3

Matrix products: default BLAS: /System/Library/Frameworks/Accelerate.framework/Versions/A/Frameworks/vecLib.framework/Versions/A/libBLAS.dylib LAPACK: /Library/Frameworks/R.framework/Versions/3.6/Resources/lib/libRlapack.dylib

locale: [1] enUS.UTF-8/enUS.UTF-8/enUS.UTF-8/C/enUS.UTF-8/en_US.UTF-8

attached base packages: [1] parallel stats4 stats graphics grDevices utils datasets methods base

other attached packages: [1] RCurl1.98-1.1 SummarizedExperiment1.16.1 DelayedArray0.12.2
[4] BiocParallel
1.20.1 matrixStats0.56.0 Biobase2.46.0
[7] GenomicRanges1.38.0 GenomeInfoDb1.22.0 IRanges2.20.2
[10] S4Vectors
0.24.3 BiocGenerics0.32.0 reshape21.4.3
[13] ggplot23.3.0 car3.0-7 carData3.0-3
[16] phyloseq
1.30.0

loaded via a namespace (and not attached): [1] jsonlite1.6.1 splines3.6.3 foreach1.4.8 assertthat0.2.1
[5] BiocManager1.30.10 GenomeInfoDbData1.2.2 cellranger1.1.0 pillar1.4.3
[9] lattice0.20-40 glue1.3.2 digest0.6.25 XVector0.26.0
[13] colorspace1.4-1 Matrix1.2-18 plyr1.8.6 pkgconfig2.0.3
[17] haven2.2.0 zlibbioc1.32.0 purrr0.3.3 scales1.1.0
[21] openxlsx4.1.4 rio0.5.16 tibble2.1.3 mgcv1.8-31
[25] farver2.0.3 withr2.1.2 survival3.1-11 magrittr1.5
[29] crayon1.3.4 readxl1.3.1 nlme3.1-145 MASS7.3-51.5
[33] forcats0.5.0 foreign0.8-76 vegan2.5-6 tools3.6.3
[37] data.table1.12.8 hms0.5.3 lifecycle0.2.0 stringr1.4.0
[41] Rhdf5lib1.8.0 munsell0.5.0 cluster2.1.0 zip2.0.4
[45] Biostrings2.54.0 ade41.7-15 compiler3.6.3 rlang0.4.5
[49] rhdf52.30.1 grid3.6.3 iterators1.0.12 biomformat1.14.0
[53] rstudioapi0.11 igraph1.2.5 bitops1.0-6 labeling0.3
[57] gtable0.3.0 codetools0.2-16 multtest2.42.0 abind1.4-5
[61] curl4.3 R62.4.1 dplyr0.8.5 permute0.9-5
[65] ape5.3 stringi1.4.6 Rcpp1.0.4 vctrs0.2.4
[69] tidyselect_1.0.0

Any ideas are welcome!

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If you don’t post the error in question (why you can’t install Hmisc) no one can help answer your question.

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library(DESeq2) Error: package or namespace load failed for ‘DESeq2’ in loadNamespace(j <- i[[1L]], c(lib.loc, .libPaths()), versionCheck = vI[[j]]): there is no package called ‘Hmisc’

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No, when you install Hmisc.

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