I am trying to understand how topGO decides a GO term is enriched. Specifically, I am trying to understand how terms not in my list (universal or my genes of interested with annotated GO terms) can be considered significant.
Like the example below. That GO ID is not in any of my lists, so how is it significant?
GO.ID Term Annotated Significant Expected classicFisher
GO:0009235 cobalamin metabolic process 1 1 0.03 0.02536