i would like to ask for a very specific problem regarding memory size in R/windows regarding the import of large size CEL affymetrix files with oligo R package, and the possibility of overcoming this problem. In detail, the total size of the CEL files (unzipped) is ~115 Gb (about 1820 CEL files-HTA 2.0 affymetrix platform).
Below is a small relative output of the problem:
dat <- read.celfiles(list.celfiles())
Platform design info loaded.
Error: cannot allocate vector of size 93.5 Gb
R version 3.3.2 (2016-10-31)
Platform: x86_64-w64-mingw32/x64 (64-bit)
Running under: Windows 7 x64 (build 7600)
 LC_COLLATE=Greek_Greece.1253 LC_CTYPE=Greek_Greece.1253 LC_MONETARY=Greek_Greece.1253
 LC_NUMERIC=C LC_TIME=Greek_Greece.1253
attached base packages:
 stats4 parallel stats graphics grDevices utils datasets methods base
other attached packages:
 BiocInstaller_1.24.0 pd.hta.2.0_3.12.2 DBI_0.6 RSQLite_1.1-2
 oligo_1.38.0 Biostrings_2.42.1 XVector_0.14.1 IRanges_2.8.2
 S4Vectors_0.12.2 oligoClasses_1.36.0 GEOquery_2.40.0 Biobase_2.34.0
which cant be increased, as my RAM is 8Gb.
Thus, perhaps the solution would be to try to a pc with a much greater memory, or i could try something here ?