Question: Outliers - to remove or to not remove that is the question
0
gravatar for bhgyu
2.6 years ago by
bhgyu30
bhgyu30 wrote:

Hi guys, 

Bit of discussion question. When would you remove an outlier from an array dataset? 

I've run quite a few plots and analysis on my data including PCA, boxplots and lumi detectOutlier. I have focussed only on removing Controls that are outliers, since Cases may be statistically significant. 

I'm now returning to wonder when it's justifiable to even remove the controls? Are there any additional analyses you may recommend? 

I'd like to be careful with removing outliers, without jeopardising leaving in an obvious one. 

Cheerio

microarray rna outliers • 480 views
ADD COMMENTlink modified 2.6 years ago by chris86390 • written 2.6 years ago by bhgyu30
Answer: Outliers - to remove or to not remove that is the question
1
gravatar for chris86
2.6 years ago by
chris86390
UCL, United Kingdom
chris86390 wrote:

I remove outliers when there is something obviously amiss with that sample because something went wrong with the array or sample prep i.e. clustering gives some really weird outlier. Other than that, I leave them.

ADD COMMENTlink modified 2.6 years ago • written 2.6 years ago by chris86390
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 16.09
Traffic: 308 users visited in the last hour