GenomicRanges::gaps() not working as expected
2
1
Entering edit mode
jfiksel ▴ 30
@jfiksel-7391
Last seen 6.9 years ago
United States

Hi all,

I am trying to use the gaps function from the GenomicRanges package, and am experienced unexpected behavior. For example, if we have the following GRanges object:

gr <- GRanges(seqnames = "chr1", strand = c("*", "*"), ranges = IRanges(start = c(1, 5), width = 3))

seqlengths(gr) <- c("chr1" = 10)

I would expect

​gaps(gr)

To return a GRanges object equal to 

GRanges(seqnames = "chr1", strand = c("*", "*"), ranges = IRanges(start = c(4, 8), end = c(4, 10)))

However, it returns a GRanges object equal to

GRanges(seqnames = "chr1", strand = c("+", "-", "*", "*"), ranges = IRanges(start = c(1, 1, 4, 8), end = c(10, 10, 4, 10)))

It doesn't seem like you would want gaps to return an GRanges object that contains ranges that are the width of the whole sequence. Is there a way to force it to return the output I was expecting?

 

Jacob

genomicranges • 1.0k views
ADD COMMENT
2
Entering edit mode
@michael-lawrence-3846
Last seen 2.4 years ago
United States

The manual explains that this is expected. In this case, you can just subset to the ranges in the "*" strand. In general, if I want to do this, I stay far away from the unintuitive gaps() and do:

setdiff(as(seqinfo(gr), "GRanges"), gr)


 

ADD COMMENT
0
Entering edit mode
jfiksel ▴ 30
@jfiksel-7391
Last seen 6.9 years ago
United States

This works perfectly, thanks so much. 

ADD COMMENT

Login before adding your answer.

Traffic: 501 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6