Hi. I asked this a long time ago but i didn't understand very well.
Can someone tell me the meaning of the sign in the "value" column in the bumphunter output included in minfi?
I have this matrix:
g <- as.factor(c(rep("c", 17), rep("t", 40))) # c for controls vs t for tumors matriz <- model.matrix(~ g) # The design matrix
And for example, if the first row has the value - 0.2...Does that mean that the methylation level is greater in tumors? In that case the comparison would be control - tumor, right?
Thank you all for your attention