Question: About the meaning of the value column in minfi package
gravatar for Antonio M.
2.0 years ago by
Antonio M.0
Antonio M.0 wrote:

Hi. I asked this a long time ago but i didn't understand very well.

Can someone tell me the meaning of the sign in the "value" column in the bumphunter output included in minfi?

I have this matrix: 

g <- as.factor(c(rep("c", 17), rep("t", 40))) # c for controls vs t for tumors
matriz <- model.matrix(~ g) # The design matrix

And for example, if the first row has the value - 0.2...Does that mean that the methylation level is greater in tumors? In that case the comparison would be control - tumor, right?

Thank you all for your attention

minfi methylation • 482 views
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