... implemented as the
computeSumFactors function in scran. Make sure you read the documentation, though.
You might also try
Bacher R, Chu L, Leng N, Gasch AP, Thomson JA, Stewart RM, Newton MA and Kendziorski C (2017). “SCnorm: robust normalization of single-cell RNA-seq data.” Nature Methods. https://www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.4263.html.
Software is available in Bioconductor devel and github: https://github.com/rhondabacher/SCnorm
These were the papers I was going to suggest :) Another one which looks at size factors and their relationship to zeros is this one: