Question: RNA-seq differential analysis for continuous phenotypes
gravatar for anpham
10 months ago by
anpham0 wrote:

I would like to do a genome-wide differential expression analysis for a continuous phenotype using counts from RNA-seq (raw counts from STAR alignment). Normally I'd use DESeq2 for the analysis and not having to do normalization. However, my understanding is that DESeq2 only models categorical phenotypes. What would software packages would you recommend for normalization of the raw count data and differential analysis for continuous phenotypes?  Thanks very much for your input.  

ADD COMMENTlink modified 10 months ago by Michael Love18k • written 10 months ago by anpham0
gravatar for Michael Love
10 months ago by
Michael Love18k
United States
Michael Love18k wrote:

See the FAQ about continuous variables in the DESeq2 vignette.

ADD COMMENTlink written 10 months ago by Michael Love18k
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.2.0
Traffic: 320 users visited in the last hour