Question: RNA-seq differential analysis for continuous phenotypes
gravatar for anpham
8 months ago by
anpham0 wrote:

I would like to do a genome-wide differential expression analysis for a continuous phenotype using counts from RNA-seq (raw counts from STAR alignment). Normally I'd use DESeq2 for the analysis and not having to do normalization. However, my understanding is that DESeq2 only models categorical phenotypes. What would software packages would you recommend for normalization of the raw count data and differential analysis for continuous phenotypes?  Thanks very much for your input.  

ADD COMMENTlink modified 8 months ago by Michael Love17k • written 8 months ago by anpham0
gravatar for Michael Love
8 months ago by
Michael Love17k
United States
Michael Love17k wrote:

See the FAQ about continuous variables in the DESeq2 vignette.

ADD COMMENTlink written 8 months ago by Michael Love17k
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