No genes with Module Membership > 0.8
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Hanna • 0
@Hanna-24408
Last seen 2 days ago

Hello! I am using WGCNA for constructing Coexpression Networks . I am now at the point where I am prioritizing genes for candidate hubs. I saw that there are different methods for choosing hub genes in a module. I saw that some people have reported using the 0.8 cutoff for MM ( correlation of the gene with the Module Eigen of the module). But I can't get any hubs for most module that can reach to 0.8. The maximum MM I can see from my modules is around 0.6. What does this suggest, that the modules are not stable enough? Should I just use the intramodular connectivity strength for hubs. Is there a cut of for that value as well?

Thanks!

wgcna WGCNA hubgenes • 23 views
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