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Showing :
Limma
•
reset
1
vote
4
replies
280
views
Bulk RNAseq analysis for
DESeq2
RNASeq
edgeR
limma
4 days ago • updated 3 days ago
Mariami
• 0
4
votes
2
replies
407
views
When to use edgeR or limma
edgeR
limma
updated 28 days ago by
Gordon Smyth
53k • written 4 weeks ago by
abzhang97
• 0
0
votes
2
replies
393
views
Combining two proteomics datasets with limpa
limpa
ProteomicsWorkflow
limma
5 weeks ago • updated 22 days ago
Andrew Pattison
• 0
5
votes
3
replies
643
views
Limma-voom sample weights and impact on DEG numbers
limma
written 7 weeks ago by
A.Barden
▴ 20
0
votes
4
replies
662
views
How does contrasts.fit do in limma to extract comparisons with a model having interaction terms?
limma
updated 5 weeks ago by
jtsy6383
• 0 • written 8 weeks ago by
Durian
• 0
2
votes
2
replies
348
views
Identifying differentially expressed genes in individual samples from a large cohort
limma
DifferentialExpression
12 weeks ago
jamie.gearing
▴ 60
0
votes
1
reply
283
views
How to model DE for RNA-seq in concordant monozygotic twins?
RNASeq
variancePartition
RUVSeq
limma
edgeR
updated 4 months ago by
Gordon Smyth
53k • written 4 months ago by
ilaria.massaiu
• 0
5
votes
13
replies
1.6k
views
Guidance on limma for pseudobulk scRNA-seq with multi-factor design
limma
RNASeq
scRNAseq
updated 4 months ago by
Gordon Smyth
53k • written 5 months ago by
abaed
• 0
0
votes
4
replies
510
views
voomLmFit fitted log-CPM values
limma
edgeR
updated 5 months ago by
Gordon Smyth
53k • written 5 months ago by
Lina
▴ 10
1
vote
3
replies
438
views
ROAST compare results with complex design
limma
mroast
roast
CAMERA
written 5 months ago by
Jiahao Tian
• 0
3
votes
4
replies
665
views
p-adjusted values in multiple comparisons
StatisticalMethod
limma
RnaSeqSampleSizeData
updated 5 months ago by
Josh
• 0 • written 6 months ago by
ocanorocabayera
• 0
2
votes
8
replies
840
views
Are voomByGroup and voomLmFit compatible?
limma
voomLmFit
voomByGroup
updated 5 months ago by
Gordon Smyth
53k • written 6 months ago by
richardallenfriedmanbrooklyn
▴ 30
1
vote
2
replies
424
views
Can limma be used with module eigengenes instead of genes?
limma
WGCNA
GSVA
written 6 months ago by
A.Barden
▴ 20
1
vote
2
replies
449
views
Difference between logFC in limma-voom and weighted limma-voom
limma
voom
weighting
6 months ago
richardallenfriedmanbrooklyn
▴ 30
3
votes
1
reply
529
views
Limpa Pipeline Order
limma
limpa
updated 6 months ago by
Gordon Smyth
53k • written 6 months ago by
abadgerw
• 0
3
votes
2
replies
508
views
Should voomWithQualityWeights still be used when the sample-specific weights vary between the groups of interest?
limma
updated 6 months ago by
Gordon Smyth
53k • written 6 months ago by
A.Barden
▴ 20
0
votes
8
replies
740
views
How to use limma to analyze complex temporal RNAseq data
timecourse
RNASeq
limma
6 months ago
Jiahao Tian
• 0
2
votes
2
replies
501
views
Limma : paired samples leading to unexpected estimates
limma
6 months ago
Basti
▴ 780
2
votes
2
replies
651
views
(Why) do limma's confidence intervals depend on topTable's p.value argument?
limma
6 months ago
sandmann.t
▴ 70
4
votes
8
replies
2.1k
views
Should Xenium pseudobulk experiments be analysed like microarrays (limma) or like RNASeq (edgeR,Deseq2, or limma-voom)
Deseq2
edgeR
limma
xenium
Voom
7 months ago
richardallenfriedmanbrooklyn
▴ 30
7
votes
9
replies
5.9k
views
competitive enrichment test yields too few significant results, self-contained too many
limma
DESeq2
fry
edgeR
7 months ago
bbao
▴ 10
0
votes
3
replies
2.6k
views
Applying lmFit(), eBayes() and topTable() for modeling associations between NMR-derived metabolic measures and various traits
limma
Bioconductor
Metabolomics
updated 7 months ago by
Gordon Smyth
53k • written 7 months ago by
anni
• 0
0
votes
4
replies
1.9k
views
How to use goana function with zebrafish genome from org.Dr.eg.db
org.Dr.eg.db
zebrafish
limma
8 months ago
Eric
• 0
3
votes
2
replies
6.5k
views
limma duplicateCorrelation appropriate where some blocks cross condition and some are in same condition?
limma
8 months ago
Geoff
• 0
2
votes
3
replies
1.7k
views
Differential gene expression analysis on haplotype-resolved diploid assembly
edgeR
DESeq2
haplotype
limma
8 months ago
Paulito
• 0
0
votes
1
reply
531
views
Typo in the help of lmFit()
limma
updated 8 months ago by
Gordon Smyth
53k • written 8 months ago by
Balazs
• 0
0
votes
2
replies
1.6k
views
Limma trend with limpa
limpa
limma
trend
updated 8 months ago by
Gordon Smyth
53k • written 9 months ago by
Alejandro
• 0
0
votes
2
replies
749
views
Limma suqeezeVar
limma
9 months ago • updated 8 months ago
Mengchun
• 0
2
votes
5
replies
1.4k
views
Dealing with heteroscedascity in limma
limma
splines
Proteomics
written 9 months ago by
Thomas
• 0
5
votes
7
replies
3.6k
views
limma correction for tumor purity
limma
9 months ago
gabriella.jacobson-eisenberg
▴ 20
4
votes
7
replies
3.6k
views
Check removeBatchEffect effectiveness
RNAseq
limma
removeBatchEffect
9 months ago • updated 4 months ago
massimo
▴ 10
0
votes
0
replies
534
views
Significant Probes and Genes differ in Probe and Region level Differential Methylation Analyses
limma
probe
DMRcate
GenomicRanges
DifferentialMethylation
9 months ago
jamiecatalano2
• 0
2
votes
1
reply
792
views
ROAST for small sets
limma
mroast
updated 9 months ago by
Gordon Smyth
53k • written 9 months ago by
Jiahao Tian
• 0
2
votes
4
replies
2.0k
views
how to use `arrayWeightsQuick()`?
limma
updated 9 months ago by
TraceMorrow
• 0 • written 10 months ago by
matthew
• 0
0
votes
3
replies
1.2k
views
Model performance for spline modelling of RNA-seq timecourses in edgeR
edgeR
limma
written 10 months ago by
skiaphrene
▴ 10
2
votes
2
replies
1.7k
views
Improving performance of edgeR and limma while adjusting for multiple confounders
edgeR
limma
updated 10 months ago by
ATpoint
★ 5.0k • written 10 months ago by
robinpaul85
• 0
2
votes
4
replies
1.1k
views
Explanation for ROAST results
CAMERA
limma
written 10 months ago by
Jiahao Tian
• 0
5
votes
3
replies
1.4k
views
Using edgeR::voomLmFit for the analysis of paired clinical RNA-seq samples with multiple cell types
edgeR
limma
voomLmFit
updated 11 months ago by
Gordon Smyth
53k • written 11 months ago by
Devin
▴ 10
2
votes
2
replies
1.8k
views
Limma - Complex 2-way multi-level contrast with paired samples
edgeR
contrastmatrix
limma
11 months ago
Elizabeth
• 0
1
vote
2
replies
1.3k
views
Differential expression of proteins using somascan data
somascan
limma
written 11 months ago by
kkeole1
• 0
2
votes
4
replies
1.8k
views
Use of limma R package with targeted proteomics for DE analysis
DEanalysis
limma
olinktargetedproteomics
11 months ago
svlachavas
▴ 840
1
vote
8
replies
2.9k
views
Combining RNAseq and microarray data using edgeR/limma-voom
limma
voom
RNASeq
edgeR
Microarray
written 15 months ago by
Adam Marstrand
• 0
4
votes
6
replies
1.7k
views
using limma trend workflow in CAMERA
CAMERA
limma
updated 9 days ago by
Gordon Smyth
53k • written 18 months ago by
Jiahao Tian
• 0
5
votes
5
replies
1.9k
views
Limma with covariates
limma
written 20 months ago by
Chris
▴ 20
12
votes
5
replies
5.6k
views
limma::voom vs edgeR::voomLmFit - when to use?
edgeR
limma
voom
RNASeq
muscat
updated 8 months ago by
Geoff
• 0 • written 2.2 years ago by
annikagable
• 0
0
votes
5
replies
8.2k
views
Pheatmap/Complexheatmap: making a continuous color scale with NAs
R
Pathways
pheatmap
limma
written 4.9 years ago by
Ridha
▴ 10
9
votes
6
replies
2.4k
views
Unbalanced experiment with multiple samples from each patient.
limma
updated 11 months ago by
canarias
• 0 • written 8.2 years ago by
Tore
▴ 10
2
votes
15
replies
4.5k
views
Annotation of Affy Porcine Gene 1.0 ST array data
limma
oligo
annotation
updated 6 months ago by
Melon Lemonat
• 0 • written 11.1 years ago by
aminbau14
• 0
4
votes
0
replies
3.5k
views
Evidence-based guidelines for use the method="robust" option in lmFit
Microarray
Normalization
Bayesian
Regression
Cancer
limma
Microarray
Normalization
Cancer
updated 9 months ago by
Thomas
• 0 • written 14.7 years ago by
Richard Friedman
★ 2.0k
0
votes
2
replies
1.7k
views
how does limma calculate the coefficients with using different design matrix?
probe
limma
15.5 years ago • updated 11 weeks ago
Gordon Smyth
53k
56 results • Page
1 of 2
Recent ...
Replies
Answer: Should I use beta1 from limpa::dpc() or limpa::dpcCN(), if they differ?
by
Gordon Smyth
53k
I tend to use dpcCN(), because it more robust than dpc() to experiments with lots of samples and big differences between samples. You coul…
Answer: Which preprocessing steps are needed before running limpa?
by
Gordon Smyth
53k
Please see the example limpa analyses given at <http://github.com/smythlab/limpa>, especially the kidney cancer case study. limpa does not…
Comment: Why does IDTaxa trainingSet for SILVA contain "_2" suffixes in the taxonomy name
by
Korneel
• 0
Thanks for the quick reply! If I understand correctly, I think if I keep track of the full lineage, I shouldn't have any risk of collapsin…
Comment: Pathway abundance data from Curatedmetagenomics
by
yesquokkan
• 0
Hello, I was also wondering about the same issue. Did you figure it out?
Comment: [DESeq2] Changing dispersion estimates between runs of DESeq2
by
colinmccornack
• 0
FWIW: This seems to be due to architectural differences between two compute nodes I was running on, specifically with the DESeq2:::fitNbino…
Votes
Answer: Subsetting data verses contrasts [DESeq2]?
A: WGCNA differences two groups 10 replicates each group
A: WGCNA sample size minimum: why?
Comment: Why does IDTaxa trainingSet for SILVA contain "_2" suffixes in the taxonomy name
Answer: Can you colour dendrogram branch clusters in pheatmap?
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