Log In
Sign Up
about
faq
Ask a question
Latest
News
Jobs
Tutorials
Tags
Users
New Post
Latest
News
Jobs
Tutorials
Tags
Users
Log In
Sign Up
About
Limit
all time
today
this week
this month
this year
Unanswered
All posts
Sort
Update
Answers
Bookmarks
Creation
Replies
Rank
Views
Votes
Showing :
STATISTICS
•
reset
10
votes
14
replies
13k
views
how DESeq calculates p-value ?
deseq
differential gene expression
statistics
p-value
updated 3.1 years ago by
Kai_Qi
▴ 20 • written 8.2 years ago by
Giard
▴ 30
8
votes
8
replies
6.7k
views
Voom transformation from counts and normalization to negative values
rnaseq
voom
limma
tcga
statistics
updated 5.6 years ago by
Ryan C. Thompson
★ 7.9k • written 5.6 years ago by
Beginner
▴ 60
25
votes
7
replies
11k
views
Effect of lfcThreshold on p-value in DESeq2
deseq2
rnaseq
statistics
updated 6 months ago by
camillab.
▴ 10 • written 6.5 years ago by
Russ Fraser
▴ 30
0
votes
6
replies
1.3k
views
regression analysis for epic array methylation data using limma
limma
Epigenetics
STATISTICS
R
23 months ago
Jitendra
▴ 10
1
vote
6
replies
2.7k
views
DESeq2 unbalanced sample size
deseq2
bioconductor
bioinformatics
statistics
updated 14 months ago by
Michael Love
41k • written 5.3 years ago by
casikecola
• 0
0
votes
5
replies
1.1k
views
Comparing sets of differentially expressed genes
deseq2
rnaseq
statistics
8.5 years ago
sunkid
• 0
3
votes
5
replies
1.4k
views
P adjusted values in Deseq2
DESeq2
Statistics
written 3.3 years ago by
Jesus
• 0
0
votes
4
replies
2.8k
views
XCMS for targeted metabolomic/lipidomics/proteomics
xcms
metabolomics
lipidomics
statistics
8.3 years ago
Titan
• 0
19
votes
4
replies
8.1k
views
Confidence intervals on edgeR logFC
edgeR
statistics
confidence interval
updated 8.1 years ago by
nwvidal
• 0 • written 9.6 years ago by
ri.lars
▴ 40
1
vote
4
replies
1.2k
views
Do the gene set statistics of the ROAST paper correspond to those implemented in the .roastEffects R function?
limma
roast
statistics
source code
gene set testing
5.7 years ago
Andrea Carenzo
• 0
0
votes
4
replies
5.6k
views
10 multiple comparisons in DESeq2
deseq2
rnaseq
statistics
updated 7.9 years ago by
Michael Love
41k • written 7.9 years ago by
kissmatee
• 0
2
votes
4
replies
1.2k
views
Removing batch effect on edgeR when interactons are looked at
rnaseq
edger
statistics
model matrix
updated 6.6 years ago by
Steve Lianoglou
★ 13k • written 6.6 years ago by
David R
▴ 90
0
votes
3
replies
922
views
batch effect in EPIC array data
statistics
Epigenetics
R
updated 14 months ago by
Lluís Revilla Sancho
▴ 730 • written 14 months ago by
Jitendra
▴ 10
8
votes
3
replies
3.2k
views
Differing topTable() results with Limma with and without specifying coefficient
limma
microarray
statistics
updated 8.0 years ago by
Gordon Smyth
50k • written 8.0 years ago by
krr
• 0
2
votes
3
replies
1.5k
views
RNAseq outlier is a critical sample
rnaseq
outlier
statistics
batch effect
updated 7.9 years ago by
Gordon Smyth
50k • written 7.9 years ago by
grastalt27
• 0
3
votes
3
replies
1.4k
views
Using alternative LFC shrinkage methods for computing p-values in DESeq2
deseq2
apeglm
statistics
updated 4.9 years ago by
Michael Love
41k • written 4.9 years ago by
zefrieira
• 0
0
votes
3
replies
1.5k
views
Reading large file (15GB) in R
R
Rstudio
Bioconducter
statistics
updated 2.2 years ago by
Sean Davis
21k • written 2.3 years ago by
Jitendra
▴ 10
0
votes
2
replies
1.3k
views
Compute test-score statistical significance using control-scores from shuffled population
statistics
hypotheses
R
8.1 years ago
Bade
▴ 310
1
vote
2
replies
2.0k
views
how to perform pre ranked GSEA in R?
r
microarray
statistics
GSEA
updated 7.1 years ago by
predeus
• 0 • written 9.1 years ago by
Nemo
▴ 80
1
vote
2
replies
954
views
What to do with microarray probes that catch multiple genes?
affymetrix microarrays
microarray
probe
statistics
updated 5.7 years ago by
James W. MacDonald
65k • written 5.7 years ago by
ravelarvargas
• 0
0
votes
2
replies
684
views
Results analysis of differential gene expression using DESeq2 package
RnaSeqSampleSize
statistics
DESeq2
updated 16 months ago by
swbarnes2
★ 1.3k • written 16 months ago by
N
• 0
0
votes
2
replies
1000
views
News:
Ascona Workshop “Biological systems: from first principles to data-driven modelling and back” 27. 3. - 1. 4. 2022
theory
modeling
statistics
ascona
Workshop
2.5 years ago • updated 15 months ago
Wolfgang Huber
★ 13k
2
votes
2
replies
7.7k
views
edgeR: How is FDR calculated for logFC? (False Discovery Rate)
edgeR
bioconductor
fdr
statistics
differential gene expression
7.4 years ago
jol.espinoz
▴ 40
1
vote
2
replies
930
views
Newbie to all of this
bioconductor
statistics
5.5 years ago
sportwoo
• 0
0
votes
2
replies
1.1k
views
comparing two GOstats result lists
gostats
statistics
updated 5.9 years ago by
James W. MacDonald
65k • written 5.9 years ago by
sven.schenk
▴ 20
1
vote
2
replies
2.7k
views
the statistical test that DESeq2 use
deseq2
statistics
updated 7.2 years ago by
Ryan C. Thompson
★ 7.9k • written 7.2 years ago by
elhamdallalbashi
• 0
1
vote
2
replies
1.1k
views
Re-calculation of Padj (P adjusted value)
statistics
Benjamini–Hochberg procedure
deseq2
updated 3.6 years ago by
Michael Love
41k • written 3.6 years ago by
Matan G.
▴ 60
2
votes
2
replies
2.8k
views
How adjusted p-values are calculated in limma
limma
r
transcriptomics
FDR
statistics
updated 4.6 years ago by
Gordon Smyth
50k • written 4.6 years ago by
Wuschel
▴ 10
1
vote
1
reply
341
views
Further analysis after limma regression output
statistics
Epigenetics
limma
updated 7 months ago by
James W. MacDonald
65k • written 7 months ago by
Jitendra
▴ 10
0
votes
1
reply
770
views
How to handle batch effect and interaction with experimental variables
deseq2
statistics
differential expression
4.4 years ago
A
• 0
1
vote
1
reply
1.3k
views
FPKM t-test vs DEseq2
DESeq2
statistics
rna-seq
updated 12 months ago by
ATpoint
★ 4.0k • written 12 months ago by
SH
• 0
0
votes
1
reply
755
views
Exclude interaction terms from the design
deseq2
statistics
modelling
updated 4.5 years ago by
Michael Love
41k • written 4.5 years ago by
polyptwo
• 0
0
votes
1
reply
318
views
DEseq2 : Complex design with a mixture of male and female mice
statistics
DESeq2
updated 4 months ago by
Michael Love
41k • written 5 months ago by
lionel.spinelli
• 0
0
votes
1
reply
964
views
Efficient resampling in GENESIS or another Bioconductor GWAS package to obtain empirical p-values?
GENESIS
GWAS
resampling
resample
statistics
5.2 years ago
naglemi
▴ 10
2
votes
1
reply
981
views
limma for gene expression analysis with big and unbalanced sample size
limma
microarray
statistics
updated 7.9 years ago by
Aaron Lun
★ 28k • written 7.9 years ago by
tati6406
• 0
3
votes
0
replies
2.2k
views
Job:
Postdoctoral Scientist, Statistical Bioinformatics and Proteomics, WEHI Australia
job
proteomics
Job
statistics
4.5 years ago • updated 4.3 years ago
Gordon Smyth
50k
1
vote
0
replies
877
views
Job:
Post-Doctoral Research Fellow, Cancer Genomics
genomics
seattle
bioinformatics
data science
statistics
Job
3.9 years ago
Fred Hutch (Recruiting)
▴ 40
0
votes
0
replies
757
views
Job:
Two Bioinformatics Fellowship Positions at US EPA
bioinformatics
toxicology
Job
sequenicng
statistics
3.7 years ago • updated 3.5 years ago
whduke
• 0
2
votes
0
replies
845
views
Job:
Multiple open positions in biomedical statistics at Eurac Research, Italy
epidemiology
statistics
bioinformatics
Job
3.6 years ago
Johannes Rainer
★ 2.0k
0
votes
0
replies
906
views
Job:
Biostatistics/Bioinformatics Research Scientist at UNC Charlotte
R
statistics
pathview
singlecellRNA-Seq
3.4 years ago • updated 3.1 years ago
Luo Weijun
★ 1.6k
0
votes
0
replies
1.1k
views
Job:
Proteomics Bioinformatician
JobPosting
Proteomics
Statistics
Job
3.3 years ago
Laura
• 0
0
votes
0
replies
884
views
Job:
Scientist/Senior Scientist, Statistical Geneticist
Sequencing
Genetics
GeneticsPed
statistics
3.3 years ago
António Miguel de Jesus Domingues
▴ 490
0
votes
0
replies
934
views
Job:
Bioinformatician at MiroBio, Oxford, UK
Transcriptomics
Bioconductor
Statistics
Job
Biocon
3.1 years ago
m.jackson
• 0
0
votes
0
replies
214
views
multipollutant models
statistics
Regression
r
limma
4 months ago
Jitendra
▴ 10
0
votes
0
replies
906
views
Job:
Biostatistics/Bioinformatics Research Scientist at UNC Charlotte
singlecellRNA-Seq
pathview
statistics
R
3.1 years ago • updated 3.0 years ago
Luo Weijun
★ 1.6k
0
votes
0
replies
2.0k
views
Job:
Full position as Statistician at ETH Zurich in Personalized Medicine Consultancy/Data Analysis
statistics
consultancy
personalized medicine
Job
9.5 years ago
Daniel Stekhoven
▴ 10
0
votes
0
replies
646
views
Job:
PhD position in Bioinformatics in Jena
Statistics
ComputationalBiology
Aging
MachineLearning
15 months ago
alena.vanboemmel
• 0
0
votes
0
replies
168
views
Job:
Statistics Lectureships at St Andrews
JobPosting
computational
statistics
8 weeks ago
Andy Lynch
▴ 120
1
vote
0
replies
623
views
Statistical test for genomic annotation by ChIPseeker
statistics
PeakAnnotation
ChIPseeker
GuangchuangYu
20 months ago
arisarkar88
▴ 40
1
vote
0
replies
746
views
Job:
Research Fellow in Prostate Cancer Proteomics (Bioinformatics/Stats/Data Analysis) - University of St Andrews
Multiomics
Proteomics
Cancer
Statistics
Bioinformatics
21 months ago
Andy Lynch
▴ 120
50 results • Page
1 of 1
Recent ...
Replies
Comment: DESeq2 output used for PCA plot on R studio
by
Aaliya
• 0
How am i making the data? I am using the DESeq2 output data which I had generated
Answer: Use of negative binomial model for exponential decay rate estimation using DESeq
by
Michael Love
41k
Sounds reasonable. For ranking genes, you could choose those with low decay rate but removing thoses where it is indistinguishable from …
Answer: Citation for edgeR user guide
by
Gordon Smyth
50k
Thanks for thinking about how to cite edgeR. Citations are indeed the main way by which the edgeR authors get credit for their work. The Us…
Comment: DESeq2 output used for PCA plot on R studio
by
swbarnes2
★ 1.3k
You are just making up data? What is the point of this exercise?
Comment: How to retrieve gene ontology GO class?
by
James W. MacDonald
65k
What do you mean by 'the information'? Do you have things in particular that you want?
Votes
Answer: Citation for edgeR user guide
Use of negative binomial model for exponential decay rate estimation using DESeq (or similar)
Answer: How to correct for age, sex, etc. from an RNA-seq data in DESeq2.
Answer: minfi::read.metharray.exp
Comment: Trying to use enrichGO
Awards
• All
Popular Question
to
Gordon Smyth
50k
Popular Question
to
i.sudbery
▴ 40
Scholar
to
Michael Love
41k
Popular Question
to
shepherl
3.8k
Popular Question
to
taur.vil
• 0
Locations
• All
France,
8 minutes ago
Singapore,
1 hour ago
WEHI, Melbourne, Australia,
1 hour ago
Melbourne, Australia,
1 hour ago
China,
2 hours ago
Traffic: 594 users visited in the last hour
Content
Search
Users
Tags
Badges
Help
About
FAQ
Access
RSS
API
Stats
Use of this site constitutes acceptance of our
User Agreement and Privacy Policy
.
Powered by the
version 2.3.6