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Showing :
StatisticalMethod
•
reset
2
votes
2
replies
558
views
DESeq2 median of ratios normalization instead of VST or rlog for ordinations?
DESeq2
medianofratiostransformation
StatisticalMethod
Normalization
dispersion
3 months ago
Linton
• 0
1
vote
2
replies
421
views
How to perform longitudinal analysis using EdgeR
StatisticalMethod
FoldChange
edgeR
RNASeq
4 months ago
Sabiha
▴ 20
2
votes
2
replies
385
views
DESeq2: Comparison of single clinical sample to 4 normals using tumour cohort to infer dispersion of single sample
GeneExpression
DESeq2
RNASeqData
RNASeq
StatisticalMethod
5 months ago
Manthos
• 0
4
votes
2
replies
572
views
DecideTest vs topTAGs in edgeR
RNAseq
StatisticalMethod
edgeR
updated 5 months ago by
Gordon Smyth
50k • written 5 months ago by
alvaroperona1
▴ 10
3
votes
2
replies
657
views
Does this RNAseq experiment require a repeated measures approach?
StatisticalMethod
RNASeqData
edgeR
DESeq2
updated 10 months ago by
Gordon Smyth
50k • written 10 months ago by
CDSPARKS
▴ 10
2
votes
3
replies
1.7k
views
deseq2 normalization and statistical method
normalization
deseq2
StatisticalMethod
updated 12 months ago by
ATpoint
★ 4.0k • written 13 months ago by
SH
• 0
2
votes
4
replies
724
views
Model comparison in mean-dispersion trend in DESeq2
DESeq2
StatisticalMethod
14 months ago
Loïc
• 0
0
votes
2
replies
714
views
Using Multi-Dimensional Scaling (MDS) to produce a vector in order to account for patient bias when constructing DGE lists from RNA-seq datasets in R?
PrincipalComponent
StatisticalMethod
edgeR
MultidimensionalScaling
Normalization
14 months ago
rcreswell01
• 0
1
vote
3
replies
878
views
Limma-voom with inverse probability weights (similar to sample weights)
limma
limma-voom
StatisticalMethod
updated 14 months ago by
Gordon Smyth
50k • written 14 months ago by
jay
• 0
0
votes
1
reply
521
views
DESeq2 paired multifactor test
DESeq2
StatisticalMethod
updated 16 months ago by
Michael Love
41k • written 17 months ago by
ijvechetti
▴ 10
0
votes
0
replies
595
views
Job:
Academic position in Non-clinical Biostatistics
JobPosting
StatisticalMethod
17 months ago
Laurent Gatto
1.6k
1
vote
2
replies
940
views
Limma adj.p.value the same for many different p.values
limmaGUI
limma
adj.p.value
StatisticalMethod
18 months ago
walkerrh95
• 0
0
votes
0
replies
861
views
Job:
Postdoctoral research scientist in computational biology/statistical genetics/functional genomics at Columbia University, USA
Alzheimer's
StatisticalMethod
Genetics
molecularQTL
FunctionalGenomics
19 months ago
gaow
• 0
0
votes
0
replies
556
views
Should I adjust p value for multi-levels (groups) and multi-variables?
StatisticalMethod
2.1 years ago
dong
▴ 10
2
votes
3
replies
3.1k
views
Differential gene expression and (adjusted) p-values
edgeR
StatisticalMethod
updated 23 months ago by
ruez.richard
• 0 • written 2.2 years ago by
tmms
• 0
6
votes
4
replies
967
views
Limma prametrization
limm
MathematicalBiology
limmaGUI
StatisticalMethod
2.3 years ago • updated 2.2 years ago
Giovanni
• 0
2
votes
7
replies
1.4k
views
EdgeR, tumor normal pair, no replicatie but multiple patients, to focus on individual patients not combined
edgeR
StatisticalMethod
2.6 years ago
Field -Ye
• 0
0
votes
2
replies
1.3k
views
To retrieve the transcript from gff file with the longest isoform
FunctionalAnnotation
StatisticalMethod
2.8 years ago
Aneesha
• 0
0
votes
1
reply
725
views
DESeq2 Design matrix
StatisticalMethod
DESeq2
updated 2.9 years ago by
Michael Love
41k • written 2.9 years ago by
Saif
• 0
6
votes
6
replies
1.6k
views
limma:arrayWeights() and the "prior.n" parameter for biological replicates? (PROTEOMICS)
Proteomics
limma
StatisticalMethod
updated 3.1 years ago by
Gordon Smyth
50k • written 3.1 years ago by
Steve
▴ 10
1
vote
3
replies
1.1k
views
How to assign random effect factor in DESeq2 desing?
StatisticalMethod
DESeq2
phyloseq
updated 3.2 years ago by
Michael Love
41k • written 3.2 years ago by
zardbid
• 0
0
votes
0
replies
1.2k
views
Why is `scale-free topology` estimated as -sign(slope) * (R^2) in WGCNA?
Network
StatisticalMethod
WGCNA
ExpressionData
3.3 years ago
jol.espinoz
▴ 40
0
votes
2
replies
714
views
p adjusted value not available
StatisticalMethod
DESeq2
updated 3.4 years ago by
Kevin Blighe
★ 3.9k • written 3.4 years ago by
marie
• 0
23 results • Page
1 of 1
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Replies
Comment: Differential peaks that were not identified in diffbind were identified in diseq
by
lonn
• 0
I tried the default normalization and got similar results as above. Perhaps I need to try identifying the difference peak without using dif…
Answer: Cannabis and KEGGgraph
by
deeenes
▴ 30
Hello, I'm a developer of the `OmnipathR` package, and I wrote [a function][1] to access certain KEGG data: library(OmnipathR) cs…
Answer: RNAseq:Technical replicates from different batches
by
Gordon Smyth
50k
I am not entirely clear what you mean by "technical" replicates in this case. Are they resequencing of the same RNA samples or are they fre…
Comment: DMR.Plot shows error "Error in simpleLoess(y, x, w, span, degree = degree, param
by
russ.bainer
▴ 10
Hi, I'm hitting this too. As far as I can tell my DataTrack is fine, but perhaps I am missing something. Notably the same code works on o…
Comment: The difference when using Limma compare between 3 conditions vs 2 conditions
by
Chris
• 0
Hi Robert, If I don't want to use all pathway in c2 gene set but only a few pathways of interested, how can I do that? So we try to get a …
Votes
Installing/switching between versions of R/Rstudio/Bioconductor on personal machine (Linux | Ubuntu)
A: Docker container with bioconductor and devtools
Answer: OrgDb for maize
Comment: significant difference of p-values with dream() after updating VariancePartition
How to tell and visualize up/down regulation of pathways from clusterprofiler gsea output
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James W. MacDonald
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shepherl
3.8k
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BioinfGuru
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Gordon Smyth
50k
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