Showing : apeglm • reset
10
votes
6
replies
5.3k
views
Log2FoldChange shrinkage method in DESeq2
deseq2 apeglm lfcshrink
updated 5.9 years ago by 41k • written 5.9 years ago by ▴ 90
5
votes
10
replies
1.2k
views
Allelic imbalance in apeglm
apeglm Allelic imbalance concept
updated 3.7 years ago by 41k • written 3.7 years ago by • 0
4
votes
2
replies
2.5k
views
Interpreting the results from lfcShrink() with apeglm in DESeq2
deseq2 apeglm lfcshrink
updated 5.6 years ago by 41k • written 5.6 years ago by ▴ 160
4
votes
4
replies
2.5k
views
RNA seq analysis using Deseq2 and apeglm lfc shrinkage
deseq2 fdrtool apeglm
updated 4.1 years ago by 41k • written 4.1 years ago by • 0
4
votes
4
replies
2.1k
views
Unexpected MAplot after apeglm shrinkage in DESeq2
apeglm deseq2 rna-seq
updated 5.5 years ago by 41k • written 5.5 years ago by ★ 4.0k
3
votes
2
replies
1.8k
views
lfcShrink function in DEseq2 and s-values
deseq2 apeglm
updated 3.7 years ago by 41k • written 3.7 years ago by ▴ 10
3
votes
2
replies
775
views
DESeq2 lfcShrink: swapping reference gives different results for the same comparison
DESeq2 apeglm
13 months ago • updated 12 months ago Daphnia • 0
3
votes
2
replies
1.4k
views
Calculate S/N ratios from apeglm for GSEA
apeglm fgsea Signal-To-Noise Ratio
updated 5.0 years ago by 41k • written 5.0 years ago by ▴ 20
3
votes
3
replies
1.4k
views
Using alternative LFC shrinkage methods for computing p-values in DESeq2
deseq2 apeglm statistics
updated 4.9 years ago by 41k • written 4.9 years ago by • 0
3
votes
4
replies
2.1k
views
Reporting S values? Reporting padj values?
deseq2 apeglm
updated 3.9 years ago by 41k • written 3.9 years ago by ▴ 20
2
votes
2
replies
1.1k
views
DESeq2 in R
DESeq2 apeglm
updated 3.2 years ago by ★ 1.3k • written 3.2 years ago by ▴ 10
2
votes
1
reply
1.1k
views
apeglm -- influence of reference level on logFC and svalues
DESeq2 apeglm
updated 3.2 years ago by 41k • written 3.2 years ago by ★ 4.0k
2
votes
4
replies
1.3k
views
What is the biological meaning of genes with FC = 0 after shrinkage
deseq2 apeglm
updated 5.1 years ago by 41k • written 5.1 years ago by • 0
2
votes
1
reply
962
views
Deactivate svalue=T in lfcShrink - DESeq2 - apeglm
deseq2 apeglm
updated 5.0 years ago by 41k • written 5.0 years ago by ★ 4.0k
2
votes
1
reply
662
views
What are the steps to use a complex model of Allelic imbalance through apeglm
apeglm complex model ASE Allelic imbalance
updated 3.7 years ago by 41k • written 3.7 years ago by • 0
2
votes
7
replies
1.8k
views
optimHess problem in apeglm/DESeq2
DESeq2 apeglm
updated 11 months ago by 41k • written 11 months ago by ★ 4.0k
1
vote
1
reply
623
views
Exceeding Over-dispersion parameter bbEstDisp
apeglm bbEstdisp allele ratio
updated 3.6 years ago by 41k • written 3.6 years ago by • 0
1
vote
4
replies
1.6k
views
Log2 fold-change shrinkage fails with lfcShrink when using the 'apeglm' method
deseq2 apeglm lfcshrink
5.7 years ago coulsonr ▴ 20
1
vote
1
reply
790
views
Why s-values instead of p-values with non-default lfcThreshold and apeglm shrinkage in DESeq2
deseq2 apeglm
updated 3.8 years ago by 41k • written 3.8 years ago by • 0
1
vote
4
replies
1.7k
views
Using different LFC shrinkage estimators for spike-in normalised RNA-seq data
deseq2 apeglm rna-seq spike-in
updated 3.7 years ago by 41k • written 3.7 years ago by ▴ 10
1
vote
2
replies
1.2k
views
Use of shrunken LFCs to address questions about the distribution of LFCs between gene categories.
deseq2 apeglm DESeq2
2.3 years ago i.sudbery ▴ 40
1
vote
5
replies
1.8k
views
DESeq2 outlier options and LFC Shrinkage
DESeq2 RNASeq RnaSeqSampleSize apeglm
updated 20 months ago by 41k • written 20 months ago by • 0
1
vote
5
replies
1.4k
views
lfcShrink probelm in many 0 count genes RNA-seq data
ashr DESeq2 apeglm
updated 2.7 years ago by 41k • written 2.7 years ago by ▴ 40
1
vote
3
replies
1.6k
views
Choosing an svalue threshold from apeglm shrunken results in DESeq2
apeglm DESeq2
updated 2.6 years ago by 41k • written 2.6 years ago by ▴ 40
1
vote
3
replies
960
views
LFC shrinkage setting negative LFC svalues to zero
DESeq2 DifferentialExpression apeglm
updated 21 months ago by 41k • written 21 months ago by • 0
0
votes
2
replies
1.2k
views
lfcShrink in DESeq2
deseq2 apeglm
updated 4.7 years ago by 41k • written 4.7 years ago by • 0
0
votes
1
reply
955
views
Plotting the most expressed genes after conducting DESeq2
DESeq2 pheatmap apeglm
updated 3.2 years ago by 41k • written 3.2 years ago by ▴ 10
0
votes
1
reply
693
views
Non-significant but high LFC after apeglm shrinkage
DESeq2 apeglm
updated 3.1 years ago by 41k • written 3.1 years ago by • 0
0
votes
2
replies
2.6k
views
DESeq2 coefficients for APEGLM-shrinkage
deseq2 apeglm
updated 5.4 years ago by 41k • written 5.4 years ago by • 0
0
votes
2
replies
789
views
Error: insufficient numeric precision during Log fold change shrinkage with apeglm
apeglm
updated 7 months ago by 41k • written 8 months ago by • 0
0
votes
4
replies
625
views
lfc direction of effect flipped for ashr, apeGLM, but accurate to biological data for non-shrunken
DESeq2 apeglm DESeq ApeGLM Ashr
updated 9 months ago by 41k • written 9 months ago by ▴ 20
0
votes
4
replies
1.1k
views
Error in Apeglm Method for Effect Size Shrinkage
deseq2 apeglm
updated 5.8 years ago by 41k • written 5.8 years ago by ▴ 40
0
votes
1
reply
163
views
lfcShrink error: the line search routine failed
apeglm DESeq2
updated 5 weeks ago by 41k • written 5 weeks ago by • 0
0
votes
2
replies
823
views
running apeglm on a normal model and multiple coefficients
shrinkage apeglm
24 months ago Frederik Ziebell ▴ 20
0
votes
3
replies
657
views
Influence of DEG in ASE analysis within apeglm
apeglm
updated 3.5 years ago by 41k • written 3.5 years ago by • 0
0
votes
1
reply
930
views
DESeq2 - shrunken LFC calculation
apeglm DESeq2
updated 3.3 years ago by 41k • written 3.3 years ago by ▴ 50
0
votes
3
replies
990
views
Using altHypothesis on apleglm-shrunken log2FoldChanges
apeglm DESeq2
3.3 years ago zefrieira • 0
0
votes
2
replies
929
views
Coefficient names for multiple group comparisons to use with lfcShrink & apeglm
deseq2 lfcShrink apeglm
updated 4.3 years ago by 41k • written 4.3 years ago by ▴ 20
0
votes
2
replies
1.2k
views
DSEQ apeglm
DESeq2 apeglm
3.2 years ago amoaristotle ▴ 10
39 results • Page 1 of 1
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Replies
Comment: DESeq2 output used for PCA plot on R studio by Aaliya • 0
How am i making the data? I am using the DESeq2 output data which I had generated
Answer: Use of negative binomial model for exponential decay rate estimation using DESeq by Michael Love 41k
Sounds reasonable. For ranking genes, you could choose those with low decay rate but removing thoses where it is indistinguishable from …
Answer: Citation for edgeR user guide by Gordon Smyth 50k
Thanks for thinking about how to cite edgeR. Citations are indeed the main way by which the edgeR authors get credit for their work. The Us…
Comment: DESeq2 output used for PCA plot on R studio by swbarnes2 ★ 1.3k
You are just making up data? What is the point of this exercise?
Comment: How to retrieve gene ontology GO class? by James W. MacDonald 65k
What do you mean by 'the information'? Do you have things in particular that you want?
Votes
Answer: Citation for edgeR user guide
Use of negative binomial model for exponential decay rate estimation using DESeq (or similar)
Answer: How to correct for age, sex, etc. from an RNA-seq data in DESeq2.
Answer: minfi::read.metharray.exp
Comment: Trying to use enrichGO
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