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clinicaldata
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Job:
Bioinformatics Scientist at NEXUS Personalized Health Technologies in Zurich
clinicaldata
translational
genomics
diagnostics
research
Job
8.2 years ago
Daniel Stekhoven
▴ 10
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1.3k
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Possible(validated) methodology implemented in R for integrating and analyzing clinical data with gene expression data in R
data integration
clinicaldata
gene expression data
PET
9.2 years ago
svlachavas
▴ 830
0
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1.8k
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Machine learning methods for feature selection and possible correlation with clinical data
machinelearning
clinicaldata
biomarkers
data integration
bioconductor
9.5 years ago
svlachavas
▴ 830
3 results • Page
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Comment: Volcano plot has many values around zero
by
Michael Love
42k
It's positive over zero or nearly so.
Answer: Volcano plot has many values around zero
by
swbarnes2
★ 1.4k
You've got genes with supposedly have a 32-fold difference, and the adjusted p-values are < 1x10-10? That seems odd.
Comment: Volcano plot has many values around zero
by
mjun
• 0
Why this cluster close to 0 with low p value is so distinctive. Is this common? What does it mean and why? Thanks
Comment: Volcano plot has many values around zero
by
swbarnes2
★ 1.4k
I don't think this is evidence that the dataset is invalid. It's evidence that your experiment is underpowered, and/or your experimental c…
Comment: Differential Expression Analysis with unbalanced batches without replication bet
by
Gordon Smyth
51k
Have you read the totalVI documentation?, which says: > **Important** > We do not recommend using totalVI denoised values in other differ…
Votes
Comment: Weird looking volcano plot
Volcano plot has many values around zero
A: Up/Down Regulated GeneList from edgeR and R
A: Up/Down Regulated GeneList from edgeR and R
A: Down/Up-regulated genes asymmetry in edgeR differential expression analysis
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Dario Strbenac
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Gordon Smyth
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Guido Hooiveld
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shepherl
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