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13.9 years ago
Matt Wilkerson
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Answer: DESEQ2 IHW and Apelgm method for Shrinkage (adding s values to FDR)
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> I got many p values that had "1.000000e+00" and padj "1" and stat of "0" when I added the Log threshold of LFC >1 and LFC < -1...is this …
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With all my love, thank you Guido, GOxploreR beeing a big ally for me.
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You didn't generate it with an experiment, you made it up:
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Your contrast is comparing LGR5 to Homeostasis. The bottom 2 are fine, it's the top one that is wrong.
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