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Comment: GSEA preranked analysis downstream of DEseq2
by
hermidalc
▴
10
Regarding GSEA preranking metric approaches, what I’ve seen, including in this thread, is that many (or most) seem to do either `logFC` or …
Comment: GSEA preranked analysis downstream of DEseq2
by
Michael Love
37k
That's fine I guess. I don't know what the meaning of that term is, which is a downside in my opinion.
A posterior effect size is an esti…
Answer: DESeq2 LFC changes sign after adjusting for surrogates
by
Michael Love
37k
Yes, controlling for covariates can change the sign of the estimated coefficient.
I'd recommend to use the code in the vignette for rem…
Answer: DESeq2 design with 6 groups
by
Michael Love
37k
I have to restrict my time on the support site for software related questions. For statistical consultation, e.g. how should i set up my an…
Comment: Which is the best type of data for correlation or survival analysis
by
Michael Love
37k
I don't know what is optimal for survival analysis. We basically have our transformations and the motivation for them (see the workflow for…
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