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Answer: Creating DESeq object and choosing a contrast
by
Michael Love
37k
If you've read over the section on interactions and are still confused what these terms mean, I'd recommend consulting with a statistician …
Comment: Can Differential Isoform expression analysis can be performed using DESeq2 packa
by
Michael Love
37k
hi,
Good question. So you can aggregate your swish isoform results to gene level (for which genes are there any significant isoforms) and …
Comment: DEseq2: working with unbalanced number of sample in tumor study?
by
Michael Love
37k
It's just that there is no breakdown point for linear models with imbalanced data. The estimates are not biased, although you lose efficien…
Answer: exomeCopy warning and error
by
Michael Love
37k
I'm guessing this data has too many zeros to produce a meaningful HMM output.
I would examine your data by eye, it may not be model-able…
Comment: Using the plotting functions of clusterProfiler / enrichplot with enrichment res
by
Kazuna
•
0
Dear Charles,
I am so impressed the way you handled this! Thank you!
Could you teach me how you created geneSets list? Did you use getgo()…
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