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Answer: Which input data is acceptable for MAST?
by
Andrew_McDavid
▴ 270
Not too familiar with SCT v2. If it also has a point-mass at zero and the non-zero component is roughly-symmetric, then it might work ok w…
Answer: segfault when using singleR with Azimuth reference
by
James W. MacDonald
67k
The training step is usually faster than the classification step, so you might try running `trainSingleR` on the reference to see if that i…
Comment: Batch Effect in DESeq2, how to control, how to remove it, how to address biologi
by
James W. MacDonald
67k
You don't. I believe Fisher has a quote that applies here. Also, please don't add to five year old posts. Start a new one.
Comment: Convert HGVS Representation back to Reference Genome Coordinates
by
Vince Schulz
▴ 160
Not a bioconductor solution, and probably not easily code-able, but there is a batch validate/convert function available here: https://vari…
Answer: How to control batch effect if Group and batch are same?
by
ATpoint
★ 4.5k
You cannot do any correction. That's the simple and only answer. You cannot distinguish true biological effect from unwanted technical vari…
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Answer: How to control batch effect if Group and batch are same?
Answer: How to control batch effect if Group and batch are same?
Comment: Convert HGVS Representation back to Reference Genome Coordinates
Answer: How to control batch effect if Group and batch are same?
Comment: Normalization RNA-seq for multiple plates
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