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Answer: miRNA differential expression analysis - treat as transcript level?
by
Michael Love
37k
If it's "ok" depends on the amount of inferential uncertainty. We have benchmarked typical gene-level methods and found that we don't gain …
Comment: RSEM - tximport; where is effective_length information used? Implications for sc
by
Michael Love
37k
@atpoint is correct -- it's not enough to say single-cell. In the tximport vignette we have a note about transcript length correction for 3…
Comment: Help with limma contrast, difference of a difference?
by
Ahdee
▴
50
thanks yes, I think this is useful and looks very nice as well. I color coded up significant up or down nc==no significant change based on …
Comment: Help with limma contrast, difference of a difference?
by
Ahdee
▴
50
all this time I did not thought to use this. VennDiagram was super useful but the the table even more useful to do some fast comparisons. …
Comment: Help with limma contrast, difference of a difference?
by
Steve Lianoglou
13k
great, let us know how it goes!
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Michael Love
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Gordon Smyth
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Nik Tuzov
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