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Comment: Question on constructing design matrix and defining contrasts for analysis by mohammedtoufiq91 ▴ 10

@gordonsmyth thank you, yes, please find the targets frame below. Basically, I want to create a design matrix and binarize by 0 and 1 to be…

Comment: WGCNA: many over and under-expressed features in modules of a signed network by andres.firrincieli ▴ 50

answered in Biostars: https://www.biostars.org/p/9564943/

Comment: Multitasking and Rbwa by Jean-Philippe Fortin • 0

Indeed, one can pass additional arguments to the `bwa_aln` function in `Rbwa`: bwa_aln(type="single", index_prefix=index_pr…

Comment: biomaRt error: database disk image is malformed by Emile • 0

UNBORKING the bioMaRt cache `biomaRt::biomartCacheClear()` also fixes the troubles with PANTHER.db installation which have also something t…

Answer: Proteomics data with NA values by Laurent Gatto 1.6k

- First, you need to assess how many missing values you have. - I would recommend not to impute your data by 0 (or any arbitrary small …

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Answer: Normalized counts from LRT or Wald test?

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