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neurodegeneration
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Job:
Seeking computational biologists with expertise in RNA-Seq and/or statistics at Immuneering Corporation, Cambridge MA and New York NY
rna-seq
CNS
Neurodegeneration
statistics
computational biology
Job
7.5 years ago
mmartin
▴ 20
2
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1.2k
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Job:
Statistical Geneticist at Denali Therapeutics, South San Francisco, CA, USA
job
genetics
drug development
neurodegeneration
Job
5.9 years ago
sandmann.t
▴ 70
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1.1k
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Job:
Job: Computational Biologists - Expanding the impact of genomic data on drug development (Immuneering Corporation, Cambridge MA and New York NY)
rna-seq
computational biology
cns disease
gene expression data
neurodegeneration
Job
6.6 years ago
mmartin
▴ 20
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Answer: DESEQ2 IHW and Apelgm method for Shrinkage (adding s values to FDR)
by
Michael Love
41k
> I got many p values that had "1.000000e+00" and padj "1" and stat of "0" when I added the Log threshold of LFC >1 and LFC < -1...is this …
Comment: Trying to use enrichGO
by
fernanda.backsouza
▴ 10
With all my love, thank you Guido, GOxploreR beeing a big ally for me. I don't know how to be grateful right now.
Comment: DESeq2 output used for PCA plot on R studio
by
swbarnes2
★ 1.3k
You didn't generate it with an experiment, you made it up: Your PCA doesn't look like a good RNASeq experiment, because it's not.
Answer: Opposite sign of LFC in count plots of DEGs (DESeq2)
by
swbarnes2
★ 1.3k
Your contrast is comparing LGR5 to Homeostasis. The bottom 2 are fine, it's the top one that is wrong. Are you sure this step isn't misla…
Comment: get BM error
by
James W. MacDonald
65k
I believe you need NCBI Gene IDs for KEGG, in which case you may need to map. The three genes you have shown here don't map, and of those t…
Votes
A: How to know if I should use voomWithQualityWeights() or not?
A: Weird results (ribosomal proteins / Y-linked genes) in limma/voom
Answer: Log-cpm values from limma
Answer: Log-cpm values from limma
Answer: Log-cpm values from limma
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