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Answer: Is it still possible to do batch correction for my data?
by
James W. MacDonald
68k
The balance doesn't matter. What does matter is that you have samples nested in batch, in which case you cannot reliably distinguish techni…
Comment: Convergence Issues and Model Selection DESeq2
by
dani.guan.3
•
0
Hi Michael,
Thank you for your quick response and suggestion.
I tried the following to determine if Batch was necessary in my design:
…
Comment: Quick two questions on limpa
by
J Kim
•
0
Thank you very much for taking the time to offer your advice and comments. I truly appreciate them.
Best regards,
J Kim
Answer: Convergence Issues and Model Selection DESeq2
by
Michael Love
43k
You could try `glmGamPoi` fitting via `fitType`:
https://github.com/thelovelab/DESeq2/blob/devel/man/DESeq.Rd#L10
This is a more rece…
Answer: Quick two questions on limpa
by
Gordon Smyth
53k
Thanks for your questions about limpa. The short answer is that you should use the default settings of the readSpectronaut() function.
The…
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