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Comment: Highly DE genes but small count difference within conditions by Michael Love 42k

Eif3j1 is a hard case, although there is separation here, there is also substantial spread. The posterior LFC is probably not that large? `…

Comment: heatmap with batch effect by James W. MacDonald 67k

When you use `removeBatchEffect` it is simply computing the mean expression for each group and subtracting that out. If you have variabilit…

Comment: Highly DE genes but small count difference within conditions by bioshot.com • 0

These are the MA plot for design=~sex+genotype and boxplots with `boxplot(log10(counts(dds)+1))` ![MA plot][1] ![sample_boxplot][2] ![box][…

Comment: miRTarRnaseq library by María Calvo • 0

Hello, Im using "Part3- Identify significant miRNA mRNA relationships for 2 time points from fold changes". In mRNA data and miRNA data, th…

Comment: heatmap with batch effect by tothuhien • 0

Hi, thank you very much for your reply. Yes what you said is true. Sorry I forgot to say that this is a just subset of samples. There are m…

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GSVA ssGSEA vs. Broad implementation of ssGSEA

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