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Comment: deseq2 normalization and statistical method
by
SH
•
0
Thank you for answering my repeated question. Although the documentation states that normalization is not necessary, I was confused because…
Answer: Reducing dataset size to improve run time for fitGAM in tradeSeq
by
Koen Van den Berge
▴
180
Hi,
We recommend keeping the entire count matrix and using the genes argument.
This way, you still use the data from all genes to do th…
Comment: Multiple issues reading in peak sets with Diffbind
by
LV
•
0
I have also had this problem today with a sample sheet that appears to be just like another sheet I previously used. I also had narrow as t…
Comment: Swish: contrasts and interactions
by
Urwah
•
0
Hi Michael,
I'm performing a very similar analysis with multiple comparisons (5 groups: 1 control group & 4 treatment - want to perform …
Answer: limma with or without intercept gives different results
by
Gordon Smyth
47k
Subsetting the data will always change the results, as it would do for any linear model or anova analysis, not just for limma. We always re…
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