User: gavin.oliver

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Posts by gavin.oliver

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Comment: C: Question about edgeR usage with one case and multiple controls
... Thanks again for all the input Aaron - it is a great help. Regarding the multiple biopsies, I absolutely agree and have pushed the same point many times, but unfortunately there is still a disconnect between standard clinical practice and the needs of researchers on the clinical threshold.  Change ...
written 3.4 years ago by gavin.oliver0
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Answer: A: Question about edgeR usage with one case and multiple controls
... Hi Aaron, I fully understand your point about the single case, however this is essentially within a research-based individualized medicine (n of 1) scenario, which ties our hands somewhat. Low expressed genes have already been filtered, but the advice is appreciated. In this 1 vs 6 setup, can we ...
written 3.4 years ago by gavin.oliver0
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Question about edgeR usage with one case and multiple controls
... Hi,    I am using a piece of pre-existing code to perform differential expression analysis with a single case and multiple (6) controls.  I am a non-statistician and am somewhat new to the minutiae of edgeR.   I include the core of the code below.  Essentially I want to confirm whether the soluti ...

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