User: alexandria.andrayas

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Posts by alexandria.andrayas

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DMRcate: Scaling factor for bandwidth
... Hello, So I am using the DMRcate package to find deferentially methylated regions. Using the dmrcate() function requires a value for C, scaling factor for bandwidth. It states that for 450k data when lambda = 1000 near-optimal prediction of sequencing-derived DMRs is obtained when 'C' is approximat ...
dmr analysis dmrcate dmr written 2.6 years ago by alexandria.andrayas0 • updated 2.6 years ago by Tim Peters80
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Design matrix for multiple interacting continuous variables in limma
... So I am looking into how duration of smoking, intensity and years since last smoked impact DNA methylation. What i want to do is create some model or design matrix that takes into account all three of these interacting factors. I was thinking something like below;   design <- model.matrix(~0 + ...
limma limma design matrix written 2.8 years ago by alexandria.andrayas0 • updated 2.8 years ago by James W. MacDonald51k

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