User: schwarzl

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schwarzl0
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Posts by schwarzl

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Comment: C: Does DESeq2 need to correct for overlapping regions?
... Hi Mike, thanks so much for your answer. Thanks, I already had a look at that and had a chat with Simon recently. There are certain reasons why a window approach would be advantageous, because of different cross-linking and binding dynamics. We will try do simulate data and do permutation test to te ...
written 8 weeks ago by schwarzl0
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Does DESeq2 need to correct for overlapping regions?
... Dear Bioconductor Support Forum, we are using DESeq2 to call differentially expressed window for overlapping sliding window on transcriptomic regions (50nt, 20nt steps for testing, this can vary). Because the different properties of our data (eCLIP), csaw is not optimal for multiple reason (differe ...
deseq2 ihw written 9 weeks ago by schwarzl0 • updated 9 weeks ago by Michael Love26k

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