User: peter.warren@verizon.net

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Posts by peter.warren@verizon.net

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Comment: C: RMA-bimodality:
... Hi, Wolfgang, Just a short follow-up. The example you provided to Noel has embedded within it two distributions. Your example is as follows: set.seed(123) n = 100000 z = 20 + exp(c(rnorm(n), 3+rnorm(n))) par(mfrow=c(1,2)) plot(density(log2(z))) plot(density(log2(z-20))) Continuing, if we separate ...
written 13.4 years ago by peter.warren@verizon.net40
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Comment: C: RMA-bimodality:
... Hi, Wofgang, Yes, mRNA abundances do indeed span the whole range. What I meant was that all the distributions of intensities I have observed seem to be poorly modeled by a single mathematical distribution (that is what I meant by my poor choice of the term "truly unimodal"). Rather, two overlaid (a ...
written 13.4 years ago by peter.warren@verizon.net40
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Answer: A: RMA-bimodality:
... Hi, Wolfgang, Noel, It is true that a non-linear transformation can change the number of nodes of the data, and that that transformation can be sufficient to explain the bimodality we see in background-corrected data. However, in my experience, the raw probe-level data is itself bimodal. When there ...
written 13.4 years ago by peter.warren@verizon.net40
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cdfName/annotation variants for hgu133a?
... Hello, I am trying to write an R function that detects the chip type of an exprset passed in, then executes different code depending on chip type. In particular, I want to detect the HGU133A, HGU133 Plus 2.0, and HGU133B. Does anyone know if there is a limited set of allowable strings for the cdfNa ...
annotation hgu133a hgu133b written 14.3 years ago by peter.warren@verizon.net40 • updated 14.3 years ago by James W. MacDonald51k

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