User: smurray

gravatar for smurray
smurray10
Reputation:
10
Status:
New User
Location:
Seattle
Last seen:
7 months ago
Joined:
2 years, 2 months ago
Email:
s************@gmail.com

Posts by smurray

<prev • 6 results • page 1 of 1 • next >
0
votes
1
answer
126
views
1
answers
Comment: C: Modeling with 'discontinuous' continuous variables, or continuous variables with
... Hi Aaron- Whoops! Let me re-ask my question in a way that doesn’t create a bigger problem than what I’m intending to ask about! (I’’ll leave my original question too, in case it helps anyone with that problem.) Let’s say I have 15 samples from one population and have a continuous variable measure ...
written 7 months ago by smurray10
2
votes
1
answer
126
views
1
answer
Modeling with 'discontinuous' continuous variables, or continuous variables with gaps
... Hello, I'm curious about the best way to work with a "spotty" continuous variable, ie a variable that is technically continuous, but there are some gaps in the values such that you might worry a model might not fit too well. For example, say I have fifteen samples in three groups, with a continu ...
limma continuous variable linear modeling written 7 months ago by smurray10 • updated 7 months ago by Aaron Lun25k
0
votes
2
answers
815
views
2
answers
Comment: C: Paired samples, two time points, two groups and adjust for a continuous variable
... Hello, Just hoping to ask a clarification question- your fourth model matrix above checks whether VO2max and expression change in the same direction- does it also check for genes whose expression changes in the opposite direction? I.e., if expression of a gene decreases between the two time po ...
written 8 months ago by smurray10
0
votes
1
answer
743
views
1
answers
Comment: C: Testing for DE genes between samples of isolated cells, accounting for expressio
... Great- thank you for helping me keep it simple! ...
written 2.2 years ago by smurray10
0
votes
1
answer
743
views
1
answers
Comment: C: Testing for DE genes between samples of isolated cells, accounting for expressio
... Thanks Aaron!  I was hoping that orange and white cat would pop up underneath my post! First, RE: your last warnings, I absolutely agree and am planning to be very cautious with interpretations of results from this technique, and will keep in mind that this strategy may not pick up differences betw ...
written 2.2 years ago by smurray10
5
votes
1
answer
743
views
1
answer
Testing for DE genes between samples of isolated cells, accounting for expression in whole tissue
... Hi all, I'm hoping to get your advice on how to test for DE genes in samples of cells isolated from a tissue, accounting for the "background" expression in the whole tissue that each sample was isolated from.  Essentially, I'd like help designing a model matrix. The particular laboratory method we ...
rnaseq limma rna-seq multiple factor design model-matrix written 2.2 years ago by smurray10 • updated 2.2 years ago by Aaron Lun25k

Latest awards to smurray

No awards yet. Soon to come :-)

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 16.09
Traffic: 300 users visited in the last hour