User: L_K

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L_K0
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Posts by L_K

<prev • 12 results • page 1 of 2 • next >
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Comment: C: Hill shape p-value histogram after differential miRNA expression analysis with D
... True, thanks for the input. I added 'fdrtool' as a tag! ...
written 8 months ago by L_K0
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Comment: C: Hill shape p-value histogram after differential miRNA expression analysis with D
... True, thanks for the input. I added 'fdrtool' as a tag! ...
written 8 months ago by L_K0
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Hill shape p-value histogram after differential miRNA expression analysis with DESeq2
... Hi everyone I have an issue with my differential miRNA expression analysis project. I have two different comparisons treatment1 (T1) vs control and treatment2 (T2) vs control and I performed standard differential expression analysis with DESeq2 and the analysis resulted in 5 significantly different ...
mirna deseq2 fdrtool written 8 months ago by L_K0 • updated 8 months ago by Robert Castelo2.3k
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Comment: C: DESeq: Design model for paired design with two treatments
... Thanks a lot. And sorry, my bad! ...
written 8 months ago by L_K0
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Comment: C: DESeq: Design model for paired design with two treatments
... Thanks a lot. And sorry, my bad! ...
written 8 months ago by L_K0
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DESeq: Design model for paired design with two treatments
... Hallo everyone As I am not exactly an expert in linear modelling and a comprehensive online search did not yield results I'd like to ask for help here: My experimental design looks as follows: 1 Condition (only individuals with a disease, no controls). Paired treatment design with pre and post tre ...
deseq2 written 8 months ago by L_K0 • updated 8 months ago by Michael Love25k
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Comment: C: Age covariate continuous vs. categorical
... Ok, got it. Thanks a lot for your time! ...
written 21 months ago by L_K0
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Comment: C: Applying SVA to RNA-Seq dataset
... Thank you very much for your input! Highly appreciated. ...
written 21 months ago by L_K0
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Comment: C: Age covariate continuous vs. categorical
... Thank you very much for your valuable answer. I'll fix the age/Year of Birth thing. However, my limited statistical knowledge doesn't allow me to understand your remark regarding the multiplicative effect of a continuous age covariate. Would it be possible to quickly elaborate on this?  Thank you. ...
written 21 months ago by L_K0
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Age covariate continuous vs. categorical
... Dear Bioconductor community   I have a question regarding the usage of age as a covariate. As proposed multiple times I tried to categorize the age covariate in order to account for it. However, as I have a rather small sample size (3 groups, n=8,n=5,n=6) it turns out that it is pretty hard to fin ...
deseq2 linear model covariates age design model written 21 months ago by L_K0 • updated 21 months ago by Michael Love25k

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