User: jurbach

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jurbach10
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Posts by jurbach

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Comment: C: lfcShrink, interactions, and ashr
... Hi Michael, The replicates are different cell sorts from the same patient at the same time point, so I've been treating them as separate samples and biological replicates. I have been summing counts from different sequence runs on the same sample. (We're not using UMIs.) What we're thinking is tha ...
written 6 months ago by jurbach10
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Comment: C: lfcShrink, interactions, and ashr
... Hi Michael, Thanks for your response. At the risk of going into too much detail, the experiment is set up like this: I have 9 patients. Patients 10, 58 & 96 experience disease relapse. Patients 16, 18, 23, 50, 55 & 75 remain in remission. For each patient, I have 3 timepoints, T1, T2, and ...
written 6 months ago by jurbach10
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lfcShrink, interactions, and ashr
... Hello DESeqers, I have two groups of patients whose gene expression is expected to change differently over time. In one group, the change in gene expression is expected to be greater or at least different, but individual patients are also expected to have different baseline levels of gene expressio ...
deseq2 contrast lfcshrink written 6 months ago by jurbach10 • updated 6 months ago by Michael Love24k

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