## User: nikosbosse

nikosbosse •

**0**- Reputation:
**0**- Status:
- New User
- Last seen:
- 9 months ago
- Joined:
- 9 months, 2 weeks ago
- Email:
- n*********@gmail.com

Profile information, website and location are not shown for new users.

This helps us discourage the inappropriate use of our site.

#### Posts by nikosbosse

<prev
• 6 results •
page 1 of 1 •
next >

0

votes

1

answer

226

views

1

answers

... Thanks a lot for your explanations
...

written 9 months ago by
nikosbosse •

**0**0

votes

1

answer

226

views

1

answers

... I understand. That helped a lot. So I can take the mean of the normalized counts for estimating mu_ij and later for estimating log q_ij = X_j* beta_i, q_ij are just the normalized counts, right?
Thanks!
...

written 9 months ago by
nikosbosse •

**0**0

votes

1

answer

226

views

1

answers

... ah yes that could be a reasonable approach for a practical implementation.
But for the purpose of really understanding how DESeq2 works internally, could you maybe please explain to me how DESeq2 manages to obtain those intial estimates hat-mu_ij?
I tried to extract this information from the sourc ...

written 9 months ago by
nikosbosse •

**0**0

votes

1

answer

226

views

1

answers

... Thank you very much for taking the time to answer and your kind and thorough reply. I very much appreciate it.
I'm not quite sure yet what approach would suit me best as I am just beginning to work with Bayesian models in general and Differential Gene Expression in particular. So my idea was, just ...

written 9 months ago by
nikosbosse •

**0**0

votes

1

answer

226

views

1

answers

... side question from a newbie: is there a way to use something like LaTeX or MathML to format this post? My attempts so far failed..
...

written 9 months ago by
nikosbosse •

**0**4

votes

1

answer

226

views

1

answer

... Please excuse if this is not the right place to post this question. I am trying to wrap my head around the exact details of the DESeq2 method in order to reimplement a simplified version of it in Stan for training purposes.
At the moment I am struggling to grasp how means for the negative binomial ...

written 9 months ago by
nikosbosse •

**0**#### Latest awards to nikosbosse

No awards yet. Soon to come :-)

Use of this site constitutes acceptance of our User
Agreement
and Privacy
Policy.

Powered by Biostar
version 16.09

Traffic: 463 users visited in the last hour