User: zefrieira

gravatar for zefrieira
zefrieira0
Reputation:
0
Status:
New User
Last seen:
1 week, 3 days ago
Joined:
1 month, 3 weeks ago
Email:
z********@gmail.com

Profile information, website and location are not shown for new users.

This helps us discourage the inappropriate use of our site.

Posts by zefrieira

<prev • 4 results • page 1 of 1 • next >
2
votes
1
answer
47
views
1
answer
Using altHypothesis with shrunken LFC values in DESeq2
... Currently, the only way to use `altHypothesis` in DESeq2 is through `results`. However, this doesn't allow to use `altHypothesis` in shrunken LFC values. I want to isolate genes with low LFC and I'm using `altHypothesis="lessAbs"` for that, but, as my LFC values were not shrunken, I think I may be u ...
deseq2 written 13 days ago by zefrieira0 • updated 12 days ago by Michael Love24k
0
votes
1
answer
73
views
1
answers
Answer: A: deseq2 pre filter rna seq
... DESeq2 filters genes based on their counts. Read the [independent filtering section][1] of the documentation. [1]: http://bioconductor.org/packages/devel/bioc/vignettes/DESeq2/inst/doc/DESeq2.html#indfilttheory ...
written 13 days ago by zefrieira0
0
votes
1
answer
101
views
1
answers
Comment: C: Using alternative LFC shrinkage methods for computing p-values in DESeq2
... Thank you very much! Is there a reason you recommend [using a stricter threshold for s-values][1]? Is this something you observed empirically? Also, are there any plans to unify the interface for getting significance levels based on shrunken LFC? Right now, there are two different interfaces: - ...
written 7 weeks ago by zefrieira0
3
votes
1
answer
101
views
1
answer
Using alternative LFC shrinkage methods for computing p-values in DESeq2
... In [this post][1], Mike Love explained the reasoning for moving LFC shrinkage into its own step using the `lfcShrink` function, decoupling testing from shrinkage. Is there any way to use `apeglm`-shrinked LFC to compute p-values (similar to using `betaPrior=TRUE`, but with the new estimator)? I kn ...
deseq2 statistics apeglm written 7 weeks ago by zefrieira0 • updated 7 weeks ago by Michael Love24k

Latest awards to zefrieira

No awards yet. Soon to come :-)

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 16.09
Traffic: 335 users visited in the last hour