User: Thomas Hampton

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Last seen:
9 years, 3 months ago
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9 years, 8 months ago
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t***************@gmail.com

Posts by Thomas Hampton

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Answer: A: Affymetrix miRNA array normalization
... Great question. At some point, quantile normalization would not be expected to work, because the true distribution of expression values under different conditions would just be too different. You'd see "differential expression" that was an artifact of normalization. I have seen RMA cause that with ...
written 9.3 years ago by Thomas Hampton20
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Answer: A: limma and Rank Products: comparison of the number of results
... I have used rank products ad limma head to head many times, so I think I understand your question. I can imagine scenarios where limma would provide a longer list, but I have not observed it myself. It is in many ways amazing that the two tests generate similar lists at all, given the enormous dif ...
written 9.7 years ago by Thomas Hampton20

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