User: david neil hayes

Reputation:
70
Status:
New User
Location:
Last seen:
14 years, 6 months ago
Joined:
15 years, 10 months ago
Email:
d*************@hotmail.com

Posts by david neil hayes

<prev • 7 results • page 1 of 1 • next >
0
votes
1
answer
329
views
1
answer
Linear response gene selection techniques
... Is there a technique in Bioconductor for selecting genes associated with a linear response such as chemotherapy response (IC50), while accounting for false discovery rates/multiple testing? I could not find an explicit procedure with this intent. Neil Hayes ...
written 14.5 years ago by david neil hayes70 • updated 14.5 years ago by James W. MacDonald51k
0
votes
0
answers
381
views
0
answers
Gene selection: association with linear response and correction for multi test
... I am interested in selecting genes associated with a linear outcome (drug dose) and including adjustments for multiple testing/false discovery. As an example, the Excel version of SAM, for example, has an implementation where the delta statistic is based on the linear regression coefficient. Am I c ...
regression limma siggenes written 14.5 years ago by david neil hayes70
0
votes
0
answers
410
views
0
answers
geneplotter and base position
... A question in 2 parts: 1. Are the "probeset base positions" in the meta-data packages (for the affy chips) derived explicitly from the affymetrix annotation provided by the company in their quarterly annotation files? 2. When there are multiple "base positions" mapped to a single probeset, is th ...
annotation geneplotter affy written 15.4 years ago by david neil hayes70
0
votes
2
answers
628
views
2
answers
normalize.invariantset usage
... I am interested in normalizing an expression matrix (not an affybatch) using the function "normalize.invariantset". I have had luck with the related normalization functions: normalize.constant, normalize.loess, normalize.quantiles (to name a few). Normalize.invariantset, unlike the other function ...
written 15.8 years ago by david neil hayes70 • updated 15.8 years ago by Laurent Gautier2.2k
0
votes
3
answers
510
views
3
answers
Answer: A: Memory Problems
... Thanks for the insight, I will try this. You are correct in that I am using a windows machine, R1.8.1. Would this problem (and many related problems) be substantially improved if I switched to a Linux system? Thanks, Neil >From: "James MacDonald" >To: , >Subject: Re: [BioC] Memory Pro ...
written 15.8 years ago by david neil hayes70
0
votes
3
answers
510
views
3
answers
Memory Problems
... Thanks to Dr. Huber for the response to my earlier question. Another matchprobes question that may have more general interest in terms of memory usage (which in my experience has been a bigger problem than processing speed) I have a folder of files, each file representing one affybatch object (whi ...
process written 15.8 years ago by david neil hayes70 • updated 15.8 years ago by James W. MacDonald51k
0
votes
2
answers
461
views
2
answers
matchprobes package:Is there a bug?
... To those who have not yet seen the matchprobes package, it is worth a look and I thank Dr. Gentleman and Dr. Huber for this addition to Bioconductor. I have the following problem with the "combine" function, however, and I wonder if it is a bug. I am able to generate the new "combined" affybatch o ...
cdf matchprobes written 15.8 years ago by david neil hayes70 • updated 15.8 years ago by Wolfgang Huber13k

Latest awards to david neil hayes

No awards yet. Soon to come :-)

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 16.09
Traffic: 122 users visited in the last hour