User: mikaelhc

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mikaelhc0
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Answer: A: EdgeR cpm: factor of 2 when adjusting library size?
... Thanks for replying so quickly - it makes more sense now! I will also try looking at the empirical logistic transformation. Best, Mikael. ...
written 3.8 years ago by mikaelhc0
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EdgeR cpm: factor of 2 when adjusting library size?
... In EdgeR, the 'log cpm' values are calculated as: ​log2(t( (t(x)+prior.count.scaled) / lib.size )) However, before that the library size is offset as: lib.size <- lib.size+2*prior.count.scaled I do not understand the factor of '2'. We add the prior to all counts, so I could understand it if we ...
edger cpm written 3.8 years ago by mikaelhc0

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Popular Question 3.8 years ago, created a question with more than 1,000 views. For EdgeR cpm: factor of 2 when adjusting library size?

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