User: Thomas Girke

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Thomas Girke1.6k
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Posts by Thomas Girke

<prev • 179 results • page 2 of 18 • next >
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Answer: A: ERROR: dependency 'GO.db' is not available for package 'systemPipeR'
... Sorry about the frustration, but this will all go away if you can fix your R/Bioc install. In a functional environment, biocLite() will install all dependency package for you automatically and you only need to do this once. On Windows (and OS X) these installs are also very fast since pre-compiled b ...
written 16 months ago by Thomas Girke1.6k
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Answer: A: ERROR: dependency 'GO.db' is not available for package 'systemPipeR'
... You need to fix your R installation or nothing will work. Getting admin permissions for the system you are on may simplify this task.    ...
written 16 months ago by Thomas Girke1.6k
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Answer: A: ERROR: dependency 'GO.db' is not available for package 'systemPipeR'
... A few suggestions. First, you want to resolve your permission issue on your system for installing packages (e.g. run with admin permissions). After this please install systemPipeR like any other Bioconductor package with: source("https://bioconductor.org/biocLite.R") biocLite("systemPipeR") A few ...
written 16 months ago by Thomas Girke1.6k
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Comment: C: SystemPipeR GO term enrichment analysis - filterDEG
... You are not saying what your cutoff for the adjusted p-value was. Note, for GO:0006954 the adjusted p-value is barely significant. Minor changes in the enrichment may bring it above the cutoff you are using, so I wouldn't be surprised if any subset of up_down was dropped in the result. If you want t ...
written 17 months ago by Thomas Girke1.6k
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Answer: A: SystemPipeR GO term enrichment analysis - filterDEG
... This could happen when a gene set is smaller than the minimum number defined under the CLSZ argument of the GOCluster_Report function, or the enrichment p-value for a GO node does not meet the threshold requirement defined under cutoff. Note, this function knows nothing about the nature or source of ...
written 17 months ago by Thomas Girke1.6k
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Answer: A: Error during installation of ChemmineOB R package
... The header files might be missing in your install of OpenBabel. On Ubuntu you want to install OpenBabel like this:  sudo apt-get install libopenbabel-dev After this, try to install ChemmineOB from R with biocLite(...) or the command-line. More detail on debugging Linux installs are provided in t ...
written 18 months ago by Thomas Girke1.6k
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Answer: A: ChemmineR package - fpSim and cmp.similarity - Tanimoto kernels
... For fingerprints you use fpSim. The cmp.similarity function has been designed for atom pairs which are integer vectors of variable length while fingerprints are binary representations of fixed length. A special case would be atom pair fingerprints which are fingerprints generated from atom pairs. He ...
written 19 months ago by Thomas Girke1.6k
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Answer: A: error when using seeFastqPlot
... Thanks for pointing this out. You are correct this error is caused by a recent change in the behavior of geom_histogram from ggplot2. I will commit the fix today. It should appear in systemPipeR release >=1.4.8 and devel >=1.5.8 tomorrow or the day after, or today via svn/github. Thomas ...
written 22 months ago by Thomas Girke1.6k
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Answer: A: GenomicAlignments: counting transcripts versus counting genes
... If you want to obtain valid exon-level counts for transcripts with summarizeOverlaps() then most likely you want to set inter.feature=FALSE. The default is TRUE, meaning the reads mapping to exons ranges shared among more than one transcript will be ignored in the read counts. The latter will be muc ...
written 23 months ago by Thomas Girke1.6k
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Answer: A: Extract three types of intergenic regions
... makeTxDbFromGFF() from GenomicFeatures fails to produce a TxDb. Something in your GFF is not meeting the expected format. This is usually fixable by debugging the GFF. However, would you mind using Biomart as source of your annotations (GFF) instead? If this is fine then please try the following whi ...
written 2.1 years ago by Thomas Girke1.6k

Latest awards to Thomas Girke

Appreciated 19 months ago, created a post with more than 5 votes. For A: heatmap.2() get matrix after hierarchical clustering
Teacher 19 months ago, created an answer with at least 3 up-votes. For A: heatmap.2() get matrix after hierarchical clustering
Scholar 19 months ago, created an answer that has been accepted. For A: SystemPipeR: alignments with ambiguous pairing were dumped.
Good Answer 19 months ago, created an answer that was upvoted at least 5 times. For A: heatmap.2() get matrix after hierarchical clustering
Scholar 2.0 years ago, created an answer that has been accepted. For A: Extract three types of intergenic regions
Scholar 2.0 years ago, created an answer that has been accepted. For A: Extract three types of intergenic regions
Student 2.6 years ago, asked a question with at least 3 up-votes. For Feature types in TxDb objects
Centurion 3.5 years ago, created 100 posts.

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