How does the empirical Bayes moderation (eBayes) in the limma pipeline work?
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Junghoon ▴ 10
@649f7bcf
Last seen 3.2 years ago
South Korea

I'd like to get a precise and intuitive understanding of how empirical Bayes moderation (conducted by eBayes function of the limma package) in the limma analysis pipeline works. I tried to read through the original paper but found it too technical and time-consuming. Could someone explain what exactly eBayes does in as precise and concise terms as possible? I don't mind mathematical/technical descriptions as far as they are short. Thank you in advance!

limma • 1.2k views
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@james-w-macdonald-5106
Last seen 7 days ago
United States

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That is exactly what I was looking for.

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