Dear BioConductor list: I am working on a small data set which came from nylon membrane spots technology. Each membrane holds 102 genes plus some controls. What I did was using vsn to normalize the data. I also like to apply IQR normalization for comparison. Are there any programs in BioConductor I can use for IQR analysis? I do not have any experience on small data sets. Any suggestions will be appreciated. Thanks! Jianping xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx x Jianping Jin Ph.D. x x Bioinformatics scientist x x Center for bioinformatics x x 3133 Bioinformatics Building x x CB# 7104 x x University of North Carolina x x Chapel Hill, NC 27599 x x Tel: (919)843-6105 x x Fax: (919)843-3103 x x E-mail: jjin at email.unc.edu x xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx